Sentences with phrase «changes in the lungs»

Secondary outcome measures included time to first exacerbation, severity of exacerbations, quality of life and changes in lung function as measured by spirometry.

«Screening with an electronic stethoscope may be able to detect early changes in lung function in individuals without symptoms of lung disease.»

According to their report, released in October, the subjects showed unusual changes in their lung tissue at roughly eight times the rate seen in a study of similarly aged transportation workers, although these could have had many causes.

Also, we would like to study what percentage of the association between respiratory tract infections and asthma can be explained by changes in lung function, and whether the associations change when we take early - life wheezing into account,» she will conclude.

All mice exhibited histopathologic changes in lungs two days after challenge including all animals vaccinated (Balb / C and C57BL / 6) or given live virus, influenza vaccine, or PBS suggesting infection occurred in all.

Creatine exacerbates the structural changes in the lungs of asthmatic mice.

Inhaling cancer - causing substances such as tobacco smoke may lead to changes in the lung tissue shortly after exposure — so - called precancerous changes.

2 grams of L - carnitine taken twice per day for two to four weeks led to positive changes in lung function and metabolism during exercise.

Thoracic radiographs provide information about heart size, status of pulmonary vasculature, and changes in the lungs.1 Evaluating the size and shape of the heart silhouette on radiographs is a key step in diagnosing and assessing severity of cardiac disease in dogs.2

X-rays and fluoroscopy may show a narrowed or occluded trachea, often with concurrent changes in the lungs.

Most veterinarians will do radiographs (X-rays) looking for fluid in the body cavities, heart size, changes in the vessels visible around the heart, and changes in the lung fields.

The veterinarian will be looking for changes in the lung sounds, respiration rates or quality, heart sounds (both rhythm and blood flow sounds), chest compressibility, signs of fluid accumulation in the chest or abdomen, and the size of such organs as the liver.

Furthermore, when mast cells degranulate chronically, permanent architectural changes in the lung, called airway remodeling, occur.

Also chest x-rays are taken to assess changes in the lungs, vessels, and heart.

Not exact matches

Merck R&D chief Roger Perlmutter said his company believes the Keynote - 024 results «have the potential to change the therapeutic paradigm in first - line treatment of non-small-cell lung cancer.»

She says that her relationship with Gurung became strained starting in February, when she says he screamed at her «at the top of his lungs» for quoting an incorrect price to a client on a blouse whose price had recently changed.

Granted, there are more benefits to reducing particulate and greenhouse gas emissions than just climate change, i.e. PM 2.5 which can be stuck in the human lung and cause cancer / respiratory issues, SO2 which contributes to acid rain (we've already eliminated the majority of this problem), as well as soot (nobody wants the surrounding area covered in ash).

Their little lungs are not quite mature enough to support them in the outside world at this stage, and their brain is changing appearance wise, taking on the grooves and ridges that make it look the same as an adults».

They have been linked to hormonal changes, birth defects, reproductive abnormalities in baby boys, and damage to the lungs, liver and kidneys.

There's no physiological requirement whatsoever to have pain in labor, unlike a baby's need to inflate its lungs after birth with a vigorous cry, and negotiate the change between fetal and infant blood circulation via a different route through the heart and pulmonary vessels.

This change in pressure also closes the hole in baby's heart that prevents the heart from pumping blood to the lungs whilst in the placenta.»

Rep. Brian Higgins called on the Trump administration to avoid policy changes that would endanger Roswell Park Cancer Institute's work on a promising lung cancer drug developed in Cuba.

Rep. Brian Higgins on Friday called on the Trump administration to avoid policy changes that would endanger Roswell Park Cancer Institute's work on a promising lung cancer drug developed in Cuba.

It's a change long sought by groups like the American Heart, Lung and Cancer associations, which believe it could accelerate an overall decline in youth tobacco use.

«Epigenetic» changes from cigarette smoke may be first step in lung cancer development.»

Scientists at the Johns Hopkins Kimmel Cancer Center say they have preliminary evidence in laboratory - grown, human airway cells that a condensed form of cigarette smoke triggers so - called «epigenetic» changes in the cells consistent with the earliest steps toward lung cancer development.

New standards that reduce sulfur in gasoline will also curb the soot that contributes to climate change and lung disease

Study lead author Dr Christopher Doughty, from the Environmental Change Institute in School of Geography and the Environment at the University of Oxford, said: «Tropical rainforests have been popularly thought of as the «lungs» of the planet.

Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.

She found that kids in Fresno were more likely to develop asthma not due to lung damage, but because changes on the surfaces of just two genes — and likely more — altered the way their lungs worked.

«By surveying thousands of individual cells, we were able to define the transcriptional landscape of lung - resident ILCs, observing changes in discrete subpopulations,» said Kowalczyk.

But Ronald Geller, director of extramural affairs at the N.I.H.'s Heart, Lung, and Blood Institute and the chairman of a committee that drafted the proposal, said that researchers would have the chance to assess the system — and recommend changes in it, if necessary — once it is in place.

If hypofractionated radiation with curative intent can reduce the treatment time for lung cancer patients by half with no greater toxicity, and with equivalent — if not better — tumor control and survival outcomes, this research could result in a change in the paradigm of how a large subset of locally advanced NSCLC patients are treated.»

It will document genetic changes in their tumours over time to examine how lung cancer evolves, and how treatment influences that process.

Two unique clinical features of heart failure in children, say the guidelines» authors, are the possible coexistence of structural congenital heart lesions, with simultaneous over-circulation to the lungs, and under - perfusion to the body (when the two circulations are linked in parallel by an intracardiac shunt or a patent arterial duct); and a change in symptom complexes over time from infancy through adolescence.

The authors speculate that the decline in lung function is attributable to the irritation that most cleaning chemicals cause on the mucous membranes lining the airways, which over time results in persistent changes in the airways and airway remodeling.

It's also through the lungs that changes in blood chemistry caused by disease can affect the odor of our breath.

One of the things that makes this a difficult task is the fact that the lungs are constantly moving through the respiratory cycle; the movements caused by the patient breathing in and out, and those of the bronchoscope itself, mean that the tissue is changing shape and location during the examination.

The second study found that the strain's extreme virulence, targeting primarily lung tissue, appeared to be linked to changes in four genes.

Some patients with non-small cell lung cancer (NSCLC) have changes in the anaplastic lymphoma kinase (ALK) gene, which can drive the development of their cancer.

«These lung function changes are comparable to the effects caused by other occupational risk factors, such as organic dusts in farming and cotton workers.

But tumors from patients with distant metastases to the lung and liver showed massive epigenetic changes that mapped to large, blocklike segments of the genome, both in the distant metastases themselves and in the section, or «subclone,» of the primary tumors they came from.

The study, «Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double - blind, placebo - controlled trail,» published online will change how clinicians understand this treatment and encourage them to consider its early use before the condition causes severe emphysema.

«This treatment has now been studied in our centre using the most sensitive measure of lung structure — a radiologic measurement of lung density — allowing us to detect changes far earlier than can be seen with standard breathing tests,» said Dr. Kenneth Chapman, Director of the Asthma and Airways Centre at Toronto Western Hospital and the Canadian research lead for the multicentre trial.

According to Harkema, the DHA could be changing the way these cells, also known as macrophages, react to the silica in the lungs and somehow alter the immune system's response.

In a new study, researchers demonstrate for the first time that recovery from bacterial pneumonia changes the tissue that was infected, seeding the lungs with immune cells called resident memory T (TRM) cells.

Global Cancer Facts and Figures, 2nd Edition, a report released in 2011 by The American Cancer Society, notes that cancers related to changing lifestyles as nations become wealthier, including lung, breast, and colorectal tumors, continue to rise in the developing world http://www.cancer.org/Research/CancerFactsFigures/GlobalCancerFactsFigures/global-facts-figures-2nd-ed

Lung cancer in particular has become the «poster child» for how research and treatment have changed, says Charles Swanton, a research oncologist at the Francis Crick Institute in London, England.

They also investigated the clinical features of these subtypes and whether there is any association with changes in genes and decline in lung function.

«Non-small cell lung cancers can be sorted in clusters by endocytic changes: Sorting cancer by defective endocytosis genes.»