Sentences with phrase «changes in this cell population»

Not exact matches

So if you take evolution in its broad sense to mean genetic changes across the population, then it might be occurring even without cell division, says Briggs.

In contrast to the conversion of alpha cells, which only concerns a small fraction of the alpha cell population, the new mechanism involving delta cell fate change is a more efficient way of offsetting the loss of beta cells and thus diabetes recovery.

Oral immunotherapy for peanut allergy induces early, distinct changes in immune T - cell populations that potentially may help researchers determine which people will respond well to the therapy and which immune mechanisms are involved in the response, a new study suggests.

In addition, they also counted the numbers of various types of single - celled organisms called testate amoebae, whose population changes depending on the amount of water in the bog, giving an indication of how wet or dry the climate was during different periodIn addition, they also counted the numbers of various types of single - celled organisms called testate amoebae, whose population changes depending on the amount of water in the bog, giving an indication of how wet or dry the climate was during different periodin the bog, giving an indication of how wet or dry the climate was during different periods.

«When we got those results everybody was really excited about it, because pulling out epigenetic changes from a cell population during an infection in vivo is really pretty remarkable,» Tarrio said.

Their recent study, which appears as the cover article in the May issue of Cancer Research, shows that mathematical models can be used to predict how different tumor cell populations interact with each other and respond to a changing environment.

The technology successfully tracked in real - time how the diversity of tumor cell populations were changing in response to particular therapies for all of the patients studied, and was highly predictive of treatment effectiveness and patient outcomes.

The researchers found that a specific stem / progenitor cell population was inhibited following radiation in mice missing Nrf2, and that alveolar type 2 cells in these mice were more likely to change into myofibroblasts — a cell type implicated in fibrosis.

This effect on growth inhibition was not due to alterations in cell cycle (Supplemental Fig. 5) nor a significant increase in the apoptotic cell populations, suggesting that RIPK2 inhibition of proliferation is independent of cell cycle or apoptotic changes.

Interestingly we observed approximately a 2-fold change in Nanog transcript levels between the two populations, and thus while the V+S + cells appear Nanog negative based on antibody staining, they still express some Nanog transcript.

To determine the length of time required for the two states to interconvert we purified populations V+S + and V − S + cells and examined the extent to which the original distribution was re-established and observed significant changes in both populations within 24 h of plating (Figure 7B).

Nevertheless, the burst properties reported in this study strongly support the idea that the deeper layers of the SC act as an optimal controller: the systematic organization of peak firing rates and burst durations as function of saccade amplitude along the motor map, the synchronous change in firing rate of recruited cells in the population, and the shaping of the temporal burst profile of a given cell with the currently planned saccade, all contribute to the generation of straight eye - movement trajectories with optimal kinematics.

Pair-wise comparisons (FDR < 0.05, > 1.5-fold expression levels) were performed between the following populations of cells to reveal non-redundant, significant changes in gene expression.

Because of small sample size, the changes in tumor - initiating cell number were not significant (P > 0.05), but these data are supportive of the in vitro findings and suggest that hypoxia may have a positive effect on the tumor - initiating cell population in ER - α — positive breast cancers and a negative effect in ER - α — negative tumors.

No significant differences were seen between the normoxic and hypoxic anoikis - resistant populations collected from MCF7 cells and a single significant gene change (PIP) was seen in T47D (Table 1) suggesting that the CSC - enriched population remains virtually unchanged following hypoxic culture and the increase in MFC, HFC, and tumor initiating cells is, therefore, due to expansion of the population, perhaps by increased symmetric self - renewal of the CSC or de-differentiation of early progenitor cells, rather than simply the acquisition of anoikis resistance in non-CSC.

(2008) Age - dependent changes in morphologically identified glial cell populations in the optic nerve of the DBA / 2J mouse model of pigmentary glaucoma (Investigative Ophthalmology & Visual Science, 49: ARVO E-Abstract 3693).

Significant changes in gene expression between anoikis - resistant and total population cells are shown in Table 1.

Overall, these results indicate that changes in ATP levels are a reliable indicator of cell death in stem cell populations upon drug insults and may have utility for hESC - based automatic screening assays.

The Penn team was surprised by the large portion of the genome that changed its chromatin signature in senescence, particularly in the tightly bound laminar regions in the senescent cell population.

MRT uses a patented combination of flow cytometry and proprietary impedance technology to measure subtle volumetric changes in white blood cell populations simultaneously.

Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles

Bioelectrical impedance vector analysis (BIVA) expresses tissue hydration status and body cell mass solely while considering the impedance vector relative to a population of healthy individuals (24); this was a valid method for detecting changes in hydration (classified as under -, normal or overhydration) and body fluid volume changes (25).

The lack of increase in T cell populations in dogs with nKCS strongly suggests that the changes in iKCS are causing the tear deficiency and not resulting from it.

* The role of the US in global efforts to address pollutants that are broadly dispersed across national borders, such as greenhouse gasses, persistent organic pollutants, ozone, etc...; * How they view a president's ability to influence national science policy in a way that will persist beyond their term (s), as would be necessary for example to address global climate change or enhancement of science education nationwide; * Their perspective on the relative roles that scientific knowledge, ethics, economics, and faith should play in resolving debates over embryonic stem cell research, evolution education, human population growth, etc... * What specific steps they would take to prevent the introduction of political or economic bias in the dissemination and use of scientific knowledge; * (and many more...)