Sentences with phrase «changes to the environment over»

We need to be powerful advocates for much - needed investment on the site, recognising that changes to the environment over the past few months have already brought many tangible gains for staff and students.

Not exact matches

Danone announced a cost - cutting plan of 1 billion euros ($ 1.1 billion) over the next three years, due to changes in Europe and a tough environment in China.

«We have some discussions we have to do with Environment and Climate Change Canada to know exactly where those caps will be, but the important part of that is that they will be declining caps year over year.»

Instead, says Copyblogger, entrepreneurs should stress over their ability to swivel and flex in reaction to the rapidly changing business environment.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Forward - looking statements may include, among others, statements concerning our projected adjusted income (loss) from operations outlook for 2018, on both a consolidated and segment basis; projected total revenue growth and global medical customer growth, each over year end 2017; projected growth beyond 2018; projected medical care and operating expense ratios and medical cost trends; our projected consolidated adjusted tax rate; future financial or operating performance, including our ability to deliver personalized and innovative solutions for our customers and clients; future growth, business strategy, strategic or operational initiatives; economic, regulatory or competitive environments, particularly with respect to the pace and extent of change in these areas; financing or capital deployment plans and amounts available for future deployment; our prospects for growth in the coming years; the proposed merger (the «Merger») with Express Scripts Holding Company («Express Scripts») and other statements regarding Cigna's future beliefs, expectations, plans, intentions, financial condition or performance.

All of this could easily change when U.S. markets open, when investors ponder the new and more volatile environment they live in, when traders decide they do not want to bear risk over the weekend, or when a weekend of pondering leads to a wave of liquidations on Monday morning.

There's also $ 135.4 million (over four years, starting in 2018) to the two lead departments, Environment and Climate Change Canada and Natural Resources Canada, for «policy, communications and engagement» for the climate plan.

Has Modern Portfolio Theory failed to deliver over the past decade because users employ long - term averages for expected returns, volatilities and correlations that do not respond to changing market environments?

The value I was assigned by my peers due to my otherness developed over time and changed depending on age and environment.

All the theory of evolution says is that life forms adapt to changes in the environment over time; that there are global changes in the gene pool of a given population of animals over time.

The Theory explains it... change over time, adaptation to diversifying environments and ebb / flow of native species.

see what you have to understand about living in a real world — a world where god is just a story and not real — its a world based on scientific and physical laws that are proven to exist and their effects are measurable... us as humans, mere animals, hold no real power or control aside thru ingenuity which allows us to change our environment to suit us... stay with me here... at this point in human history we ceased to change to suit our environment and started changing it to suit us — thats destruction of the earth to suit one species — that should go over well...

For over 80 years NABI has represented the interests of the beverage alcohol import community by assuring access to the US market and alerting the import community to changes in the regulatory environment.

With Steam Infusion allowing more control over the steam flow rate, we change the operating characteristics of the Vaction ™ Unit from a gentle introduction of steam to a disruptive high shearing process environment.

In high - capacity production environments, forward - thinking manufacturers look to minimize or eliminate the need for change - over and at the same time plan for system adaptability for product sizes of the future.

the obvious fact is that the club began to stagnate in football terms a decade ago after the CL semi against man utd and has been in outright retreat over the last 3 years... some fans were calling for wenger to leave in 2011 - 12 as it was clear he could not cope with a more competitive environment others have been more tolerant, hanging on to fa cup glory and hoping that he would somehow self correct his weak and erratic management style but most now realise that is not possible and that the club will deteriorate further under his management so also want him gone, that has left a hard core of wenger loyalists who are either fixated with the past (selecting episodic good and bad times to justify wengers decade long failure) or too frightened of the future to contemplate a change (with selective reference to failed managerial changes by way of justification) or both, to conclude, through a mixture of panglossian fatalism and corporate philosophising, how lucky we are to have such an honourable and educated man in charge... along with their confused references to club loyalty and addiction to computer games these are troubled souls who need our sympathy and concerned medical advice... SO JUST F OFF STOCK UP ON CANNED SOUP AND GO SUPPORT ASTON VILLA ON FIFA!

What's more, the concept of which foods offer an appropriate complement to the diet of a breastfed infant as well as the food environment, including a booming baby food industry, have changed dramatically over the past 50 years, Turner - Maffei pointed out.

The resulting data is used to compare relative abundance of seabirds over time — to help us understand populations within the sanctuary and their possible impacts on local ecosystems and as a barometer for other changes in the environment.

So many recent cultural shifts — a growing sense of alarm over childhood (and adult) obesity, a new interest in where our food comes from and how its production affects our health and environment, concern about climate change and the need to source food locally — all point in that direction.

It's just that offering fruit (and vegetables) in a vacuum, with no nutrition education, no over encouragement, no change in the child's home environment, and in a culture that relentlessly promotes junk food, it's easy to see why so many kids sill refuse to eat it.

Republicans on a congressional science committee are asking state Attorney General Eric Schneiderman to fork over a number of records related to his probe of climate change and what Exxon Mobil may have known about its effects on the environment.

AG Eric Schneiderman has shot down a request from Republican members of a congressional committee that he turn over a number of records related to an investigation into climate change and what ExxonMobil may have known about its effects on the environment.

The bill was granted a second reading by 3444 votes to three, but several Tory MPs stood to cast doubts on the existence of climate change, raising concerns over the party's commitment to the environment.

In a report published this morning, the Environment, Food & Rural Affairs Committee argued Defra must now concentrate on rural communities, given that its climate change brief has been shifted over to the new Department of Energy and Climate Cchange brief has been shifted over to the new Department of Energy and Climate ChangeChange.

Lancaster University scientists worked with colleagues from China and Germany to collect and analyse samples from ice cores which had been laid down over 30 years, to show how residues of Perfluoroalkyl substances (PFASs) in the environment have changed over time.

In an about - face, the agency agreed that global warming is happening; that humans, by pumping greenhouse gases into the atmosphere, are responsible; and that the American environment is likely to change dramatically over the next century.

«It's all about the time scale over which evolution occurs in relation to the timing of the changes now occurring in the environment, because there are likely to be mismatches,» he said.

«If we can understand how the landscape has changed over decades and what that does to water quality, human health, and ecosystem health, we can begin to make predictions for the future,» said senior author Kathleen Alexander, professor of wildlife conservation in the College of Natural Resources and Environment and a Fralin Life Science Institute affiliate.

«We can use this information to look at questions about climate change or human impact on environments by seeing how, over time, the ranges of insect species have changed.»

It follows that macroevolution may, over the longer - term, be driven largely by internally generated genetic change, not adaptation to a changing environment.

Mention the environment or climate change, and people's eyes tend to glaze over.

Over generations, the animals changed and adapted themselves to their respective environments, finding their way into as yet unoccupied ecological niches.

«This study is about understanding how evolution works, which tells you how species adapt to changing environments over many generations,» says Pedro Beltrao, a research group leader at EMBL - EBI.

According to the Center for Health and the Global Environment at Harvard Medical School, climate change over the coming decades is likely to increase rates of allergies, asthma, heart disease and cancer, among other illnesses.

Not everything from St. Paul Island is muddy: The team collected vegetation to compare it with ancient pollen and other clues to the environment stored in the sediment cores to learn how the island has changed over time

Unlike many populations of animals that undergo genetic changes over numerous generations and improve their camouflage against the environment, sand fleas from the different beaches begin life as a planktonic larval stage and so are likely to come from the same gene pool.

The results, published in the March issue of Frontiers in Ecology and the Environment, show how bears» diets have changed over the years as the National Park Service took different approaches to managing bears and people in Yosemite.

«MAVEN's findings reveal what is happening in Mars» atmosphere now, but over time this type of loss contributed to the global change from a wetter environment to the dry planet we see today,» said Rahmati.

Some of the methods used to predict at risk species are trend - based — an indicator of what happens gradually over time — while others are trait based, which uses signs of climate change in the current environment.

«The removal of a soil sample from its natural environment also means that the same sample can only be measured once, so the traditional (destructive) method is not suited to measuring changes at a point over a period of time..»

To enact a fully fledged Delta Plan, says Saleemul Huq, a senior fellow in the climate - change group at the International Institute for Environment and Development in London, will require several billion dollars over the next few years.

But most initiatives share the goal of providing an immersive environment to equip participants with specific knowledge and skills over a few days or weeks — and hopefully offering a nice change of pace from the daily grind of research and some fun along the way.

The fact that Neanderthals — typically associated with hunting large prey over short distances in woodland settings — were seemingly unable to catch and kill such creatures is compounded by rapid changes in the environment.

«Ridiculously cute mouse lemurs hold key to Madagascar's past: Genetic analysis of world's smallest primates tells us how the island's environment changed over time.»

As scientists and manufacturers develop more tools to analyze metabolomics in more detail, we learn more about biological systems — how they function in healthy and disease states, as well as how they change over time and in different environments.

Minute change by minute change — over long periods of geological time — organisms are shaped to the exigencies of their environment.

Several reasonable explanations arise given these results: (1) all players were exercising, and exercise produces predictable changes in skin habitat conditions that are likely to affect bacterial communities over time; (2) players were acquiring microbial transients from the built environment; and (3) players were coming into repeated physical contact with their teammates and those from opposing teams, often using the sampled area of their upper arms, and potentially sharing portions of their skin microbiomes.

Their work is starting to reveal how diverse ecological communities can change and adapt over time, putting to the test ideas developed out in the field about how organisms adapt to one another as well as to their environment.

To understand Earth's changing radiation environment: Regular monitoring of the stratosphere over California shows that cosmic rays have intensified more than 10 % since 2015.