Dansgaard et al. (1989); increasingly abrupt
changes were seen on further study, Johnsen et al. (1992); Grootes et al. (1993); jumps of Greenland snow accumulation «possibly in one to three years» were reported by Alley et al. (1993); see Alley (2000); five - year Younger Dryas steps: Taylor et al. (1997); a Younger Dryas temperature step in less than a decade was found to be hemisphere - wide since methane gas changed as well, Severinghaus et al. (1998).
An ERG can be used to diagnose PRA before the characteristic
changes are seen on ophthalmic exam.
Abrupt climate
change is seen on decadal to millennial scales.
Not exact matches
On a broader level, he will
be seen as just one of many who stood at the forefront of a broad cultural
change, one that eventually affected the health and lives of millions of people.
The
change is likely to
be gradual at first, and it
's not yet clear which markets will
see it after the U.S., but over time, shoppers will begin to notice star ratings and top reviews
on product pages
changing.
(
See This isn't always a bad thing and it
's part of the psychology — or pathology if you prefer — that also makes it possible for entrepreneurs to quickly get over their past hiccups and get
on with their main job of making history and
changing the world.
«
On the other hand, financial conditions do
change, and it
's our collective responsibility both to monitor those
changes and to communicate truthfully to the public what we
see.»
While cities shouldn't
change based solely
on Amazon's wishes, many
saw the experience as a way to benchmark themselves against other similar - sized cities around the country and
see where they might
be falling short.
Davidson recommends using www.finra.org: «Type your adviser's name into the FINRA database and you'll learn what securities licenses this person actually has and, even more important, whether or not any complaints, disciplinary actions, suspensions, or very frequent
changes of employment appear
on his or her record... You'll want to
see a completely clean record... Even a single complaint, and certainly any disciplinary action,
is a major red flag.»
TiOKé Staffing & amp; lt; / div & amp; gt; & amp; lt; div & amp; gt; Our (Amadeusz Topka & amp; amp; amp; Faisal Afzal) Company's New Year Resolution
is to start
on changing the current Car Freshener market and expand it towards new heights by providing a product which includes style and fine fragrance whether you
are driving in a sedan...
See MoreFaisal Afzal & amp; lt; / div & amp; gt; & amp; lt; div & amp; gt; «@smbizdoitbetter: What
is your businesses New Year's Resolution?
The result
is a shift in overall leadership styles, where executives now want to
see hard numbers before they'll sign off
on changes.
«What you
see with a
change in leadership
is this loss
on the part of the market of knowing whom to listen to,» Page said.
«I think it
's a shock to
see the school system getting
on board with the
changing Ireland we live in and it becoming the «norm,» which helps the cause against bullying so much,» Ryder told INSIDER.
And insofar as the government
is about to «
change the rules,» taking the five - year prohibition
on license transfer and extending it a further five years... as you
change the rules you effect the marketplace, and disrupt the balance that government strives to offer, so I
see a refund as a valid mechanism and a cunning tactic for both sides.
Nather noted that it
was interesting to
see that the attackers had not
changed their IP addresses — the equivalent of street addresses
on the Internet — since its earliest beginnings in 2012.
To
be a truly collaborative leader and colleague, you need to
be willing to get clear
on what collaboration means for you and others, address non-collaborative behaviors when you
see them, and offer feedback when you
see someone making the positive
changes you've requested to create a more collaborative environment.
May also called for big
changes to who sits
on boards so that they include employees, as
is the case in some European countries: «In practice, [board members]
are drawn from the same, narrow social and professional circles as the executive team and — as we have
seen time and time again — the scrutiny they provide
is just not good enough.
It remains to
be seen whether the
changes will have a cooling effect
on hot housing markets or how much more difficult it will
be for would -
be homebuyers to secure mortgages.
The restrictions «really did have a minor impact
on our throughput and so consequently, I don't anticipate
seeing a tremendous increase in our throughput once it
's lifted, based
on some of the
changes we've made already,» said TransCanada
's head of liquids Paul Miller
on a conference call.
Martin Moen, the director general at Global Affairs Canada who oversees North American trade policy, told a conference in Ottawa earlier this month that it would
be «very difficult to
see a path forward» for NAFTA if the U.S. continued to insist
on changes that would constrain cross-border commerce, such as a the suggestion that the value of U.S. government contracts won by Canadian and Mexican firms should match the value of contracts American companies secure in Canada and Mexico.
High - tech marketers
are able to configure and
change what we
see on the fly.
This means that we'll know how best to reach them
on social media for any future announcements that we consider important, like Google updates or big
changes in the world of SEO, or when it
's most likely they'll
see shares of our best content.
The startup fundraising landscape
saw its most significant
change in eight decades when the Securities and Exchange Commission voted to lift the ban
on general solicitation, a move which allows entrepreneurs to tell potential investors that they
are seeking funding for their companies.
So we set up a project with a bunch of sociology and psychology students, and a test lab where these PhD students could watch kids playing games, and this company would
change which games they released based
on what our PhD students
were seeing.
«We
are optimistic that the
changes we have
seen thus far have Tiffany
on a better path for success.»
Instead, use these numbers as a jumping - off point to determine where you should begin engaging, but
be sure to measure your performance
on each site to
see when and if you need to
change course.
These products sold well, but Scott could
see that
changes were on the horizon.
The evolution of how we find content
on the web has
been just as dramatic as the
changes we
saw in the internet itself.
We do not
see a material
change to our thesis
on the name, and think there continue to
be questions
on the overall trajectory of the business.»
Jacobs: We've started to
see the conversation around criminal justice
change from what it had
been forever, but do you think that
change needs to happen
on the local and state level first before we get to a national consensus?
On Monday, as Irma weakened over Georgia, Bossert used a White House briefing to offer more hints of an emerging climate resilience policy, while notably avoiding accepting climate
change science: «What President Trump
is committed to
is making sure that federal dollars aren't used to rebuild things that will
be in harm's way later or that won't
be hardened against the future predictable floods that we
see.
About $ 5 billion
changed hands in Snap stock — that
's roughly
on par with what Twitter
saw on its first day.
Your areas of impact could
be, but
are not limited to, your wish - list of
changes you would like to
see in your life, going
on a trip of a lifetime to your dream destinations, positive
changes in any of your relationships, and problems or neglected opportunities that you
see in the world around that you can no longer put off addressing.
«About 60 per cent of goods sent from Canada and Mexico to the U.S. would
see virtually no
change in the tariffs assessed
on them if the U.S.
were to withdraw from NAFTA,» the Scotiabank economists conclude.
Yet, at the Upfront Summit, Johnson and his other panelists warned Silicon Valley that they must keep up with the
changing demographics of the nation, or they too will miss out
on the opportunities that Johnson had
been seeing over the past 20 years.
ESPN, for example,
is seen by many analysts as
being protected from the winds of
change because it has a stranglehold
on sports - related content — something viewers still seem willing to pay for.
I
am looking forward to
seeing how this inclusive mindset continues to grow and play out across leadership and business strategy — especially as we look into the new year toward Davos, which will focus
on strengthening global cooperation and inclusivity across regions and industries, as well as how organizations communicate differently with customers to empower those around them to
be agents of the
change, not merely products of it.
I heard there
are some
changes being tested to the Facebook UI, and then
saw this Local Market
on the app.
If you think
changing specific elements could enhance your design, create another version based
on your hypothesis and run an A / B test to
see if there
is any improvement in checkout rates with the new design.
The impact of this
change in capital gains holding period
on crowdfunding platforms remains to
be seen.
With more people blending personal and business relationships online, and more companies reaching out to customers through social networks (
see this month
's cover story
on Zappos
's strategy), it feels to me that the definition of what
's considered «professional»
is changing.
Bogle
sees some positive
changes in investment managers voting
on behalf of their clients» interests, but it
is «moving with glacial speed,» he told me, because fund managers «don't like controversy.»
But for 3D printing to catch
on the rapidly
changing manufacturing industry, it will have to
be seen by companies less as a fascinating technological upgrade and more as an everyday business decision.
«We don't
see suddenly reverting back until there
is substantial policy
change on the monetary policy side.»
The two
were also agreed that larger national discussions need to
be held around climate
change, economic development and accommodation of aboriginal rights and title — and that LNG development should
be seen as an opportunity to move
on these issues.
Once you choose a specific flight, you'll
see predictions
on whether the price
is expected to
change — and by how much — to make sure you
're getting the best deal.
Technology
is changing businesses everywhere, but special attention now centers
on service - oriented industries, which already account for more than 50 percent of global GDP and
are likely to
see enormous opportunities for innovation in coming years.
«I
'm not sure I
see any scope for
change on something like the so - called divorce bill.
The global demonstration, planned in the wake of the Women's March
on Washington,
is aimed at countering the «mischaracterization of science as a partisan issue» —
see climate
change, vaccines, and GMOs — and the dubious policy that has arisen as a result.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may
be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required
on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not
see advantages of these products over other therapies and may therefore
be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to
changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact
on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).