Not exact matches
Actual results and the timing
of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing
of, and risks relating to, the executive search process; risks related to the potential failure
of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies
of eptinezumab sufficient to achieve a positive completion; the
availability of data at the expected times; the clinical, therapeutic and commercial value
of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture
of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights
of others; the uncertain timing and level
of expenses associated with Alder's development and commercialization activities; the sufficiency
of Alder's capital and other
resources; market competition;
changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.
Among the factors that could cause actual results to differ materially are the following: (1) worldwide economic, political, and capital markets conditions and other factors beyond the Company's control, including natural and other disasters or climate
change affecting the operations
of the Company or its customers and suppliers; (2) the Company's credit ratings and its cost
of capital; (3) competitive conditions and customer preferences; (4) foreign currency exchange rates and fluctuations in those rates; (5) the timing and market acceptance
of new product offerings; (6) the
availability and cost
of purchased components, compounds, raw materials and energy (including oil and natural gas and their derivatives) due to shortages, increased demand or supply interruptions (including those caused by natural and other disasters and other events); (7) the impact
of acquisitions, strategic alliances, divestitures, and other unusual events resulting from portfolio management actions and other evolving business strategies, and possible organizational restructuring; (8) generating fewer productivity improvements than estimated; (9) unanticipated problems or delays with the phased implementation
of a global enterprise
resource planning (ERP) system, or security breaches and other disruptions to the Company's information technology infrastructure; (10) financial market risks that may affect the Company's funding obligations under defined benefit pension and postretirement plans; and (11) legal proceedings, including significant developments that could occur in the legal and regulatory proceedings described in the Company's Annual Report on Form 10 - K for the year ended Dec. 31, 2017, and any subsequent quarterly reports on Form 10 - Q (the «Reports»).
After surveying our membership about the proposed
changes to the taxation
of CCPCs and how they might affect the
availability of capital and active Angel support for entrepreneurs, we found that possible outcomes include decreased incentive and capital for Angels to invest and decreased access to early - stage capital, which may adversely influence the flow
of funds and
resources to Canadian entrepreneurs.
The
changed and intensified land use has also markedly reduced the
availability of nectar
resources in the landscape.
Such offices shall engage in cooperative research, development, and demonstration projects with the academic community, State Climate Offices, Regional Climate Offices, and other users and stakeholders on climate products, technologies, models, and other tools to improve understanding and forecasting
of regional and local climate variability and
change and the effects on economic activities, natural
resources, and water
availability, and other effects on communities, to facilitate development
of regional and local adaptation plans to respond to climate variability and
change, and any other needed research identified by the Under Secretary or the Advisory Committee.
To provide information to stakeholders addressing these issues, the USGS Groundwater
Resources Program made a detailed assessment of groundwater availability of the Central Valley aquifer system, that includes: (1) the present status of groundwater resources; (2) how these resources have changed over time; and (3) tools to assess system responses to stresses from future human uses and climate variability an
Resources Program made a detailed assessment
of groundwater
availability of the Central Valley aquifer system, that includes: (1) the present status
of groundwater
resources; (2) how these resources have changed over time; and (3) tools to assess system responses to stresses from future human uses and climate variability an
resources; (2) how these
resources have changed over time; and (3) tools to assess system responses to stresses from future human uses and climate variability an
resources have
changed over time; and (3) tools to assess system responses to stresses from future human uses and climate variability and
change.
Similar examples can be found across the content areas: The
availability of abundant primary
resources can
change the nature
of history class.
Therefore, the accessibility and
availability of technology
resources may be an influential reason for teachers»
change in technology PD preferences and needs.
Connell, Sean; Kroeker, Kristy; Fabricius, Katharina; Kline, David; Russell, Bayden We explore how ocean acidification combines with complex environmental
changes across a number
of scales, highlight the multiplicity
of factors and complexities that cause variation, and raise awareness
of CO2 as a
resource whose
change in
availability could have wide ranging community consequences beyond its direct effects.
Availability of resources such as usable water will also depend on changing rates of precipitation, with decreased availability in many places but possible increases in runoff and groundwater recharge in some regions like the high latitudes and
Availability of resources such as usable water will also depend on
changing rates
of precipitation, with decreased
availability in many places but possible increases in runoff and groundwater recharge in some regions like the high latitudes and
availability in many places but possible increases in runoff and groundwater recharge in some regions like the high latitudes and wet tropics.
Climate
change, global economic instability, overpopulation, erosion
of community, declining biodiversity, and
resource wars, have all stemmed from the
availability of cheap, non-renewable fossil fuels.
Older people are at much higher risk
of dying during extreme heat events.136, 50,241,233 Pre-existing health conditions also make older adults susceptible to cardiac and respiratory impacts
of air pollution25 and to more severe consequences from infectious diseases; 257 limited mobility among older adults can also increase flood - related health risks.258 Limited
resources and an already high burden
of chronic health conditions, including heart disease, obesity, and diabetes, will place the poor at higher risk
of health impacts from climate
change than higher income groups.25, 50 Potential increases in food cost and limited
availability of some foods will exacerbate current dietary inequalities and have significant health ramifications for the poorer segments
of our population (Ch.
The additional processes included in the JULES model will provide a more complete picture
of water
resources of South Asia than previously possible, allowing quantitative analysis
of the effects
of changes in river flow and glaciers on water
resources and the implications
of these
changes on water
availability for irrigation and therefore crop yields.
The report highlights that natural
resource constraints, especially climate
change and the limited
availability of productive land and water in some regions, pose substantial challenges to producing food at affordable prices.
Impacts on food accessibility and
availability, and personal safety are leading to
changes in
resource and wildlife management and in livelihoods
of individuals (e.g., hunting, travelling)(high confidence).
Such offices shall engage in cooperative research, development, and demonstration projects with the academic community, State Climate Offices, Regional Climate Offices, and other users and stakeholders on climate products, technologies, models, and other tools to improve understanding and forecasting
of regional and local climate variability and
change and the effects on economic activities, natural
resources, and water
availability, and other effects on communities, to facilitate development
of regional and local adaptation plans to respond to climate variability and
change, and any other needed research identified by the Under Secretary or the Advisory Committee.
(1) to provide new and additional assistance from the United States to the most vulnerable developing countries, including the most vulnerable communities and populations therein, in order to support the development and implementation
of climate
change adaptation programs and activities that reduce the vulnerability and increase the resilience
of communities to climate
change impacts, including impacts on water
availability, agricultural productivity, flood risk, coastal
resources, timing
of seasons, biodiversity, economic livelihoods, health and diseases, and human migration; and
Overall, there is low confidence in the projections
of specifically how climate
change will impact future precipitation on a subregional scale, and thus in projections
of how climate
change might impact the
availability of water
resources.
Climate
Change and Himalayan Cold Deserts: Mapping vulnerability and threat to ecology and indigenous livelihoods The remote cold desert stretches
of high altitude Himalayas, having a fragile ecosystem are characterized by complex interplay
of climatic and geo - morphological processes,
availability of limited natural
resources and economic conditions leading to accelerated
resource degradation and associated environmental consequences [continue reading...]
This rapid
change might affect the
availability of water
resources by altering the rates
of evaporation and precipitation.
A growing body
of scientific research concludes that increased temperatures and
changing precipitation patterns are altering the timing and
availability of water
resources in the western United States [3].
It is certain that competition for
resources will become more severe as the
availability of resources (e.g., soil and water) becomes more variable and less predictable as the climate continues to
change (25).
Himalayan Glaciers: Climate
Change, Water
Resources, and Water Security explains that changes in the availability of water resources could play an increasing role in political tensions, especially if existing water management institutions do not better account for the social, economic, and ecological complexities of th
Resources, and Water Security explains that
changes in the
availability of water
resources could play an increasing role in political tensions, especially if existing water management institutions do not better account for the social, economic, and ecological complexities of th
resources could play an increasing role in political tensions, especially if existing water management institutions do not better account for the social, economic, and ecological complexities
of the region.
Thus, we highlight how ocean acidification has the potential to influence competitive abilities via
changes in
resource availability, with implications for the stability and persistence
of the system as a whole.
In addition to natural calamities, the Institute will focus on «creeping» environmental hazards — including climate
change, land degradation, degradation
of the social environment, population displacement, and
changing resource availability and quality — which imperil communities in a more gradual but equally detrimental and multifaceted way.
Is this a question for which the answer might have
changed over the years, given the burgeoning
availability of legal
resources and specialization
of practices?
About Blog This blog deals with the decline
of the
availability of natural
resources, climate
change, ecosystem disruption and why all that is happening.
• Advise staff
of any
changes in policy and procedures, allocate
resources, plan work schedule and assign work • Train current and new staff members, conduct performance reviews and make recommendations regarding corrective actions and dismissals • Proactively assist departmental manager with scheduling for entire department for various training courses to ensure service level is met • Create and distribute various reports to staff and peers Collector III (September 2007 to present) • Assisted non prime borrowers in bringing their loan current using one
of the variety
of programs offered customized for individual financial needs • Assisted team manager with maintaining and distributing month end numbers to peers needed for individuals to achieve individual as well as team monthly goal • Proactively created and facilitated various training classes to assist peers with negotiation skills, creating a sense
of urgency as well as curing past due mortgage loans • Peer coached Prime and HAD agents on negotiation skills, overcoming objections and handle time Financial Service Advisor / Relief Team Manager (March 2006 to September 2007) • Proactively contacted Card members that were deemed likely to attrite, educated them on their current terms and offered competitive balance transfer rates based on their individual credit history • Assisted with new hire training and development • Created reports assisting peers with agent
availability which increased team results by 20 % • Provided feedback to marginally performing associates to improve both individual and department performance in percentage
of contacts to attempts, phone
availability and sales rate
As climate
change, drought, mismanagement and over-allocation
of water in Australia has significantly decreased the
availability and quality
of water
resources, these issues impact on Indigenous peoples» ability to fulfil our cultural and customary responsibilities on sea and water country.
With the widespread
availability of designer
resources online, that has
changed.