Not exact matches
As part of the
Microbial Ecology Lab, he will help survey the many distinct habitats of Shedd's animal
populations, analyzing how unseen members of complex ecosystems are impacted by
changes in the environment, advancing the understanding of how these tiny microbes affect animal health.
A new study delineates a sequential pattern of
changes in the intestinal
microbial population of patients recovering from cholera in Bangladesh, findings that may point to ways of speeding recovery from the dangerous diarrheal disease.
It's currently a challenge to do this kind of
microbial redesign — antibiotics reduce
microbial burden but fail to induce major
changes in bacterial composition, and from fecal transplant studies in the gut we know that bacterial
populations return to a baseline
population even after a major shift — so more work is needed to attempt a durable
change in the vaginal microbiome.
In mice, this dickering includes
changes to the gut
microbial population that ultimately lead to even more inflammation in the brain.
«Advances in genetic sequencing technologies now allow us to find patterns in large, diverse
populations of microorganisms, see how they associate with specific individuals, and understand how they
change over time in a way we couldn't just a few years ago,» said Knight, who leads the UC San Diego Microbiome and
Microbial Sciences Initiative.
«But what this study does is allow us to explore further, now that we're clearly
changing the gut
microbial population and have new bugs that are more prevalent in mice with altered amyloid deposition after antibiotics.»
Together, these interactions — from enzymes to minerals to
populations — represent
microbial networks as ever -
changing systems, much like what's observed in experiments.