Sentences with phrase «changing risk environments»

Next week, I hope to provide more color for you on our changing risk environment.

Not exact matches

«This incident has really contributed to changing the strategic environment in which these key pipeline infrastructure decisions are going to be made,» says Mark McClelland, head of North American research for risk - analysis firm Maplecroft.

our operations in foreign countries expose us to political and currency risks and adverse changes in local legal and regulatory environments;

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Carry trades are popular when there is ample risk appetite, but if the financial environment changes abruptly and speculators are forced to unwind their carry trades, this can have negative consequences for the global economy.

All of this could easily change when U.S. markets open, when investors ponder the new and more volatile environment they live in, when traders decide they do not want to bear risk over the weekend, or when a weekend of pondering leads to a wave of liquidations on Monday morning.

If we look to federal jurisdiction, the National Energy Board has issued a series of decisions since 2010, with input from Environment and Climate Change Canada, requiring offsetting for caribou and other species at risk and rare or sensitive habitats.

May 1, 2018: Yesterday, the Minister of Environment and Climate Change Canada released the first ever section 63 report under the Species at Risk Act, (SARA), where the Minister found that outside of protected areas, provinces and territories have failed to protect almost all of boreal caribou critical habitat.

While reaching for yield has been successful in the past, we suggest increasing credit quality, increasing liquidity and reducing risk in an environment where the Fed's policy changes introduce a very different forward - looking outlook.

MLPs are subject to significant regulation and may be adversely affected by changes in the regulatory environment including the risk that an MLP could lose its tax status as a partnership.

At MWM, our client commitment is to preserve capital, manage risk, and grow your assets in an ever - changing global environment.

It's one simple system to streamline operations and minimize compliance risk in the ever - changing cannabis regulatory environment.

These factors — many of which are beyond our control and the effects of which can be difficult to predict — include: credit, market, liquidity and funding, insurance, operational, regulatory compliance, strategic, reputation, legal and regulatory environment, competitive and systemic risks and other risks discussed in the risk sections of our 2017 Annual Report; including global uncertainty and volatility, elevated Canadian housing prices and household indebtedness, information technology and cyber risk, regulatory change, technological innovation and new entrants, global environmental policy and climate change, changes in consumer behavior, the end of quantitative easing, the business and economic conditions in the geographic regions in which we operate, the effects of changes in government fiscal, monetary and other policies, tax risk and transparency and environmental and social risk.

CEO Jean - Laurent Bonnafé observed that in a challenging environment for the entire banking industry, BNP Paribas succeeded in maintaining its client franchise, profitability and strong risk - management culture, while adapting the organization to changing market conditions and regulation.

The Changing Concept of Sudden Infant Death Syndrome: Diagnostic Coding Shifts, Controversies Regarding the Sleeping Environment, and New Variables to Consider in Reducing Risk.

Climate change amplifies existing risks to our natural resources by forcing plants and animals to adapt rapidly to a changing environment.

With regard to the infant's sleeping environment, the authors conclude that the major influences on risk were from factors which would be amenable to change.

Hazardous cosleeping environments and risk factors amenable to change: case - control study of SIDS in south west England.

The Changing Concept of Sudden Infant Death Syndrome: Diagnostic Coding Shifts, Controversies Regarding Sleeping Environment, and New Variables to Consider in Reducing Risk.

Drawing on a wealth of research (including the Minnesota Longitudinal Study of Risk & Adaptation), Paul challenged the ways we often try to predict or measure success and helped change the public conversation about the kinds of experience and environments children need from infancy to adulthood.

In order to make it the safest possible and eliminate some of these added risks they need to be willing to make some dramatic changes in their own sleep environment since baby will be there with them.

The changing concept of sudden infant death syndrome: Diagnostic coding shifts, controversies regarding the sleeping environment, and new variables to consider in reducing risk.

American Academy of Pediatrics: «The Changing Concept of Sudden Infant Death Syndrome: Diagnostic Coding Shifts, Controversies Regarding the Sleeping Environment, and New Variables to Consider in Reducing Risk.»

WHEREAS, there are significant long - term risks to the economy and the environment of the United States from the temperature increases and climatic disruptions that are projected to result from increased greenhouse gas concentrations and the resultant climate change;

AAAS CEO Rush Holt urged the Trump administration on Tuesday to work with the scientific community to reduce the risk climate change poses to human health and the environment, reiterating that climate change is real and its impacts are already evident.

However, he cautioned, «In a business and technology environment that is changing so rapidly, there are risks in hoping that one's specialization will forever be in demand.»

«We hypothesized that changes in the environment and lifestyle reassign functional significance of existing polymorphisms, turning some of them into risk - associated and others into disease protective,» Gorlov said.

Climate change and recent heat waves have put agricultural crops at risk, which means that understanding how plants respond to elevated temperatures is crucial for protecting our environment and food supply.

«The crane fly link was made as part of several longer - term studies — funded by The Natural Environment Research Council and Defra — investigating blanket bog ecosystems across several UK upland sites, including the Yorkshire Dales, Peak District and North York Moors.Dr Heinemeyer, who is currently leading a # 1m Defra - funded SEI project to further study the impacts of climate change and management on blanket bogs, said it wasn't only rare birds that were at risk from climate change.

Harvard University's health and global environment initiative sponsored a talk today among evangelicals and scientists on climate change and will host one on Friday on the health risks of climate change.

If you want to change the risk profile of people, you need to work on the environment.

Some of the methods used to predict at risk species are trend - based — an indicator of what happens gradually over time — while others are trait based, which uses signs of climate change in the current environment.

Genetic risk factors may make some individuals more susceptible to these changes in the environment, and thus more prone to obesity.

While some environmental leaders now cautiously support development of more nuclear reactors (which are free of fossil fuels) to help stave off climate change, others remain concerned that the risks to human health and the environment are still too high to go down that road.

The researchers suggest that living in a rural or urban environment may change the intestinal microbiome, due to different exposures early in life, resulting in decreased or increased risk

Heart failure linked to temperature spikes Schneider and her collaborators published two studies this year, one in the journal Heart examining short - term temperature changes and heart health, and another paper published in Science of the Total Environment looking at how pollution and temperature influence health risk.

As many as 65 percent of people in some countries haven't even heard of climate change, and perceptions of risk often depend on local temperatures as much as beliefs about humans» role in the changing environment, a new study finds.

Abstract: Coastal communities in tropical environments are at increasing risk from both environmental degradation and climate change and require urgent local adaptation action.

For example, it's more likely that changes within many genes, combined with how these genes interact with one another and the environment, are collectively responsible for an increased risk of developing PTSD.

The consequences of climate change are being felt not only in the environment, but in the entire socio - economic system and, as seen in the findings of numerous reports already available, they will impact first and foremost the poorest and weakest who, even if they are among the least responsible for global warming, are the most vulnerable because they have limited resources or live in areas at greater risk... Many of the most vulnerable societies, already facing energy problems, rely upon agriculture, the very sector most likely to suffer from climatic shifts.»

«The region is profoundly affected by climate change — including loss of sea ice, acidification of the ocean, and increased access for industries that pose significant risks to the ocean environment.»

They want a company who is going to look out for their business on a day to day basis such as; help with risk management, advise them on changes to industry regulations, and a provider who updates their technology to meet the demands of the changing payments environment.

In the midst of this environment, Kovacic made it her goal to create equitable learning conditions that successfully supported a culture of academic risk taking, intellectual curiosity, and development of both scholars and citizens — all in an effort to change the lives of students like Brittany.

Controls are a means to an end — they are a dynamic and fluid set of tools which evolve over time as an academy's objectives, environment, technology and corresponding risks change.

Students also need to be able to assess their own level of competence as well as correctly to assess the hazards and the likelihood of changing levels of hazard in an environment; for example, if a group comes to a swollen river which they need to cross, there is clearly a risk which has to be assessed.

I think the second step is that if, or once, we convince people that there's a need for a change, we need to create an environment which is risk - free so that the people who are doing the change, the courageous leading - edge instructors in institutions are okay if not everything works out fine the first time around.

The study also concluded that the favorable changes in daily environment and teacher behavior were linked to positive changes and accelerated growth of at - risk preschoolers» early literacy skills.

This interdisciplinary research network is dedicated to understanding the opportunities and risks for learning afforded by today's changing media ecology, as well as building new learning environments that support effective learning and educational equity.

Curricular changes to incorporate explicit instruction on neuroplasticity, metacognition, and practical strategies to transform classrooms into positive learning environments in which students feel safe, accepted, encouraged to take intellectual risks, empowered to take charge of their learning, and motivated to persist through the work required to progress academically;

To succeed as a risk - taking school, we must not only create a safe environment for students to make mistakes, but be flexible enough to be able to change course if something is not right.