Sentences with phrase «characteristics of human disease»

Characteristics of human disease such as erythema migrans, carditis, arthritis, and neuropathy of the peripheral and central nervous systems have all been observed in macaques [28].

Eran Andrechek, a physiology professor in the College of Human Medicine at Michigan State University, has discovered that many of the various models used in breast cancer research can replicate several characteristics of the human disease, especially at the gene level.

Not exact matches

The loss of a single gene in mice can affect social behavior and impair their brains» ability to filter out distractions — both characteristics of several neurological diseases in humans.

Scientists and the public are now considering the ethics of a tool that might be used someday to edit the genes in the human germline (eggs and sperm) to create new characteristics that could be passed on to subsequent generations, or to correct diseased or otherwise «unwanted» genes.

Another key concern is the possible orientation of research towards human enhancement, going beyond disease prevention into the engineering of «desirable» genetic characteristics.

First author Antonio Di Meco and colleagues used a triple transgenic (3xTg) mouse model that displays an AD - like phenotype, including cognitive decline, and Aβ and tau neuropathology characteristic of the disease in humans.

The researchers used mouse models that mimic the disease characteristics of pulmonary hypertension and pulmonary fibrosis in humans to study the effect of triciribine, which inhibits production of a protein called Akt1.

«In this study, we were able to observe the existence of microscopic disease and low numbers of bacteria, which would be difficult to «see» in humans but could possibly be the cause of the variable and nonspecific symptoms that are characteristic of post-treatment Lyme disease syndrome.

«The capability of this method to separate exosomes without altering their biological or physical characteristics potentially offers new pathways to assess human health as well as the onset and progression of diseases,» said Subra Suresh, co-corresponding author of the paper and president - designate of Nanyang Technological University Singapore, the 21st Century Professor of Biomechanics in Medicine at the University of Pittsburgh Medical School, and former president of Carnegie Mellon University.

Researchers have produced knockout mice with characteristics similar to humans suffering from a wide range of disorders, including cancer, heart disease, neurological disorders and even obesity.

The Disease Ontology has been developed as a standardized ontology for human disease with the purpose of providing the biomedical community with consistent, reusable and sustainable descriptions of human disease terms, phenotype characteristics and related medical vocabulary disease coDisease Ontology has been developed as a standardized ontology for human disease with the purpose of providing the biomedical community with consistent, reusable and sustainable descriptions of human disease terms, phenotype characteristics and related medical vocabulary disease codisease with the purpose of providing the biomedical community with consistent, reusable and sustainable descriptions of human disease terms, phenotype characteristics and related medical vocabulary disease codisease terms, phenotype characteristics and related medical vocabulary disease codisease concepts.

The relative specificity of this cognitive deficit points to an issue of cognitive inflexibility in the BAC model, which would be consistent with deficits characteristic of Huntington's Disease in humans.

Two relatively recent gene variants help humans survive with deficiencies characteristic of agricultural diets; another genetic shift appears to help fight the dental cavities that arose with farm - based staples; another changes the way humans digest fats; dozens of others help fight the diseases that came with living at higher densities.

Thus, universal characteristics of preagricultural human diets are helpful in understanding how the recent Western diet may subject modern populations to chronic disease: Before the development of farming and the domestication of livestock practices, dietary choices would have been necessarily limited to minimally processed wild plant and animal foods.