Sentences with phrase «characterize gene expression changes»
Other labs have used DNA microarray analysis to characterize gene expression changes in this model.
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«Our hypothesis was, if a disease is characterized by certain changes in gene expression and if a drug causes the reverse changes, then that drug could have a therapeutic effect on the disease,» he says.
To characterize changes in gene expression that are triggered by death, we identified genes that were differentially expressed between pre-mortem and post-mortem blood samples, the latter being collected at several different PMI intervals (Fig. 6b, Supplementary Table 8 and Supplementary Data 2).
RNA - seq technology offers a rapid and scalable approach to characterize how gene expression changes in response to experimental manipulations, and is applicable across a wide range of taxa.
The aim of his research was to use microarray gene expression data in order to characterize ageing in different human tissues and identify the age at which major changes in genetic expression profiles occur.