Sentences with phrase «characterized by hypoxia»

His studies revealed that the blood and lymphatic vasculature, fibroblasts, immune cells and the extracellular matrix associated with tumors are abnormal, collectively creating a hostile tumor microenvironment characterized by hypoxia, low pH and high interstitial fluid pressure.

Not exact matches

The irregular vasculature of solid tumors creates hypoxic regions, which are characterized by cyclic periods of hypoxia and reoxygenation.
91 Normal functioning of adipose tissue is often (but not exclusively) impaired in obesity 91 and can be characterized by excessive hypertrophic adipocyte growth, elevated macrophage infiltration, hypoxia and dysregulated lipid storage.92
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