Sentences with phrase «characterized cells»

«This suggests an even more significant «lookout» role for these recently characterized cells than previously thought.»

«One of the most difficult points for anyone starting out in the field is getting hold of well - characterized cells,» he says.

They began by characterizing the cell composition, protein expression, metabolism, and electrical activity of neurons from each region in vitro.

Now, a team of scientists at the Icahn School of Medicine at Mount Sinai have developed the Just EGFP Death - Inducing T - cell, or JEDI T - cells, which enable the visualization of T - cell antigens, allowing researchers to study T - cell interactions with different cell types, model disease states, and finally determine the functions of otherwise poorly characterized cell populations.

«It will be necessary to characterize the cells in more detail... for their tumorigenicity upon transplantation,» he wrote in an email.

The Characterized Cell Line distributes well characterized and validated cell lines to researchers across the world and offers cell line validation using short tandem repeats STR profiling.

We identify and characterize every cell and see how each immune cell works as part of a system to prevent or exacerbate disease.

Our proprietary antibody discovery technology quickly characterizes every cell in complex immune systems, powering our selection of drug targets, identification of drug candidates and preclinical assessment of efficacy.

Our group establishes a new approach to cell mechanics characterizing cells as an actively prestressed material.

Most research at the time focused on characterizing these cells and their functions in greater detail.

The commentary highlights the possible fundamentally different and even opposing functions of intestinal fibroblast subpopulations in regulating inflammation and tumour formation and underscores the need to further characterize these cells to reveal new mechanisms underlying pathogenesis of chronic inflammation and cancer.

When we further characterized the cell lines derived from the iPSC - like colonies, we observed that they possessed hESC - like morphology, growing as flat colonies with large nucleo - cytoplasmic ratios, defined borders and prominent nucleoli (Figure 4C).

Sten Linnarsson (Karolinska Institutet / SciLifeLab), Joakim Lundeberg (KTH / SciLifeLab) and Mats Nilsson (Stockholm University / SciLifeLab) is leading the investigations, which aims to characterize cell types of brain, lung and heart tissue using single - cell RNA sequencing, and and make a three dimensional map of where the different cell types are located in the embryo.

To further characterize these cells, we sorted the CD45 - expressing cells by immunomagnetic bead separation, and measured cell purity by flow cytometry (Figure 1a — b).

Four — Culturing stem cells allows you to better characterize the cells as to type and function.

The Court characterized cell phones as minicomputers filled with massive amounts of private information, which distinguished them from the traditional items that can be seized from an arrestee's person, such as a wallet.

First, although it was possible to characterize the relative proportion of mononuclear white blood cell types in the blood samples provided using the techniques developed by Accomando et al. (2014) and Houseman et al. (2012) to characterize cell type variation, and we found that protective parenting was associated with the relative proportion of monocytes in the mononuclear white blood cell sample, that proportion was not associated with youth reports of their health in young adulthood.

Not exact matches

============ CONCLUSIONS A. # 1 is an accepted scientific fact, by theists and atheists, importantly: it does not in and of itself describe how we got from initial proto - cell to current complexity B. # 2 has a severe flaw, as phyletic gradualism is dead, and punctuated equilibrium (the fossil record being characterized by new species appearing fully formed) is an accepted fact C. # 3 is the ONLY theory that has support from the fossil record

Crosslinked polyethylene is a high density closed cell foam characterized by a compact feel and resistance to water that enables the material to be fabricated, thermoformed or compression molded in many ways.

It gives red blood cells their colour (which is why iron deficiency anemia is often characterized by paleness of the skin).

It is characterized by ganglion cells missing from part of the colon.

Each factor involved in the tumor response — whether it is the speed with which chemotherapeutic drugs reach the tissue or the degree to which cells signal each other to grow — is characterized by a mathematical equation that captures its essence.

Compared with mice with cells from healthy people as well as non-chimera mice, those whose brains had human schizophrenia cells were more afraid to explore a maze, more anxious, more antisocial, less able to feel pleasure (from sipping sugar water), worse at remembering, and more sleepless — all of which characterize people with schizophrenia, too.

Chronic HIV infection results in exhaustion of the immune system, a phenomenon characterized by dysfunctional HIV - specific killer T cells.

In another study, Rezende helped functionally characterize the specific fragments of the cell surface protein, Als5p, that allows the pathogenic fungus, Candida albicans, to bind to its host.

Grouping T cell receptors for a given epitope revealed underlying common features that characterized the bulk of the repertoire,» said first author Pradyot Dash, D.V.M., Ph.D., a staff scientist in Thomas» laboratory.

Lambert - Eaton syndrome, an autoimmune disorder frequently associated with small - cell carcinoma of the lung, is characterized by impaired evoked release of acetylcholine from the motor nerve terminal.

Characterized by tremors, rigidity, difficulty walking and other symptoms, Parkinson disease is caused by the destruction of brain cells that produce the neurotransmitter dopamine.

«Just as normal cells with the same genome differentiate into many different cell types, a single tumor characterized by specific genetic mutations can contain many different types of cells — stem - like and more differentiated cells — with the difference being rooted in their epigenetic information.

Their analysis of more than 4,000 individual tumor cells, the largest effort to date in brain tumors, finds three developmental categories of cancer cells — one resembling neural stem cells and two characterized by sets of genes indicting paths towards differentiation.

The first step of the investigation consisted of isolating the fungus from brood cells and characterizing it in the laboratory.

A newly characterized group of pharmacological compounds block both the inflammation and nerve cell damage seen in mouse models of multiple sclerosis, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nature Neuroscience.

A blood cancer characterized by the rapid growth of abnormal white blood cells, AML is typically treated with chemotherapy, in some cases followed by a stem cell transplant.

Characterized by malignant alterations in the blood - forming stem cells in the bone marrow, ALL is the most common form of childhood cancer.

In rare cases the bite also can cause a severe illness called systemic loxoscelism, characterized by a blood clotting disorder and hemolysis, destruction of red blood cells.

Type 1 diabetes, formerly known as juvenile diabetes, is characterized by the immune system's destruction of the beta cells in the pancreas.

«Graphene's bonding effect on platinum nanoparticles characterized: Lower costs in fuel cell production?.»

Extensive studies have found that 20 % to 30 % of breast cancers are characterized by over-expression of HER2, which makes the cancer cells grow and divide faster, leading to a cancer that's more aggressive and more likely to be resistant to the standard of care.

In mice, this form of lipodystrophy was also characterized by «whitening» of brown fat cells, a loss of white fat, and signs of metabolic syndrome, including insulin resistance, fat tissue inflammation, dyslipidemia (elevated cholesterol and fat), increased resting energy use, and increased markers of cardiovascular disease.

CTL1 is also found in animal cells, Chao noted, and thus the study concluded that «characterizing CTL1 as a new regulator of protein sorting may enable researchers to understand not only ion homeostasis in plants but vesicle trafficking in general.»

Using tumor samples from the Women's Healthy Eating and Living clinical trial, researchers identified stem - like tumor cells as being characterized by low levels of the molecule p53 upregulated modulator of apoptosis (PUMA).

Quintana - Murci and colleagues used RNA - sequencing to characterize the way that immune cells, known as primary monocytes, derived from 200 people of self - reported African or European ancestry would respond to attack by a bacteria or a virus.

«Discovery of new T - cell subtype opens window on rheumatoid arthritis: Finding flows from researchers» use of high - tech tools to deeply and efficiently characterize patient cells.»

Attacking its victim's white blood cells, E. chaffeensis causes a disease called ehrlichiosis, characterized by fever, malaise, body aches, and, if left untreated, organ failure.

Both groups isolated carefully characterized blood stem cells from genetically marked mice.

While the disease can take many forms, recent advances have better characterized how lymphoma cells proliferate and interact with other cells and tissues, leading to the development of powerful, targeted therapies with fewer side effects than traditional approaches.

Some researchers have questioned those results, saying that the apparent starting cells are not well characterized.

«Further research is needed to characterize how we can potentially remove or block this protein to stop the proliferation of leukemia cells.»

By identifying novel genes and molecular pathways involved in shaping a taste cell's function, these findings may someday allow scientists to treat taste disorders, characterize new taste qualities, or even fine - tune a person's taste perception to encourage healthier eating.

Diabetes is characterized by high blood sugar levels poorly regulated by either inadequate insulin production or because cells to not respond properly to the regulating hormone.