Sentences with phrase «charge of its active site»

Yet properties of the molecule — in particular involving the charge of its active site — have stymied potential developers of inhibitors.

Not exact matches

Most importantly, they found that the active site of TTLL7 is ideally positioned to contact the negatively charged «beta - tail» of beta - tubulin, one of the two protein building blocks of the microtubule polymer (alpha - and beta - tubulin).
The researchers knew they needed a catalyst that could not only support active and efficient chemical reactions, but one that could also provide a stable interface with the semiconductor, allow the charge generated by the absorption of light from the semiconductor to be efficiently transferred to the sites doing catalysis, and permit as much light as possible to pass through.
This has been viewed as a «relaxation» of the enzyme active site that is charged with iron - hydrides that are needed for the N2 reduction reaction.
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