Sentences with word «checkpoint»

The success of immune checkpoint inhibitors in cancer therapy continues to grow, but a complete understanding of their underlying mechanisms is still lacking.

These experiments were essential to understanding the effect of gemcitabine on cell cycle and the effective scheduling of checkpoint inhibitor for maximal malignant cell kill.

It's a form of what's called behavioural analysis, and it's one of many new elements that may appear at security checkpoints in the near future.

Features: Over 30 levels with checkpoint system Simple controls and design Daily challenges and high scores Music, sound effects, and customizable color palettes...

Prior to joining SRS, Jeff served as CFO at Checkpoint Systems, a NYSE publicly traded global technology company.

You'll need them to go through airport security checkpoints as well as in emergencies like missing belongings or canceled flight re-booking.

Combination of Turnstone's oncolytic viral immunotherapy with checkpoint inhibitors showed promising results in preclinical testing

Each level has a number of performance and the player will often switch between characters levels.If the player dies during the level they again can be played on the last checkpoint levels on one of four problems, and each level can be repeated.

In a retrospective analysis of clinical trial data, they found that melanoma patients with highly aneuploid tumors were less likely to benefit from immune checkpoint blockade therapy than patients whose tumors showed fewer chromosomal disruptions.

Although the former may require targeting additional antigens, the authors said, the latter may be overcome with existing drugs that target immunosuppressive molecules, such as checkpoint inhibitors used to successfully treat other cancers.

Also, as someone who actually DOES have to bring food and liquids through security checkpoints for actual, true, medical reasons, I take offense to the idea that you are abusing this medical provision for your own, personal loophole.

In addition, long delays at security checkpoints on the first day of full competition frustrated spectators, some of whom missed the competitions they had wanted to see.

A recent visit to the heavily guarded border between South and North Korea reminded me of going through Checkpoint Charlie at the Wall between East and West Berlin in the 1970s and 80s.

With 60 challenges in all, ranging from checkpoint races to slalom style driving, these are a great way to get to know your F1 cars.

If players want the classic experience of breathlessly trying to make it to the next checkpoint before the game ends abruptly, there's a Nightmare mode available.

We therefore advise all passengers travelling to the U.S. to arrive at the airport three hours prior to departure to ensure they can proceed through all airport checkpoints in good time.

Once you have collected your bags and are ready to exit, you'll have to go through the last checkpoint where you'll need your printout.

Some of Berlin's biggest sights such as Checkpoint Charlie, Potsdamer Platz or the Brandenburg Gate are an easy walk away too.

As players explore environments, they'll pass checkpoints which save their progress.

The major drawback with the game being on PS2, though, is that since the machine does not have a hard drive for mass storage, the game can't actively save checkpoint saves in the middle of the level, and you will be forced to save the game manually to your memory card.

In each race, players are looking to stay ahead of the timer by hitting checkpoints before time expires.

I had to restart checkpoints on multiple occasions after an hour of running around trying to solve a puzzle just to realize that a portion was glitched under the map or not completely loaded.

«This suggests that the benefits achieved by checkpoint blockade result from a transient revving up of exhausted T cells, not a permanent reshaping of their state,» Haining says.

The West Bank has 280 military checkpoints through which Palestinians must pass.

Drivers can expect increased road patrols and sobriety checkpoints along roadways throughout the state, as well as a stepped - up effort to ticket distracted drivers using handheld electronic devices.

Through her Clinical Team Grant, Dr. Bhardwaj and Sacha Gnjatic, Ph.D., are investigating the relationship between checkpoint immunotherapy, chemotherapy, and mutations in advanced bladder cancer, to guide vaccine development and inform combination treatment approaches.

But surprisingly there is no race type in which players must reach checkpoints within a time limit and / or before other racers.

Set goals that include a plan of action with various checkpoints along the way to measure your progress.

It's still much better than having to start the level from the very beginning every time you die, but I do think having the ability to continue from your last checkpoint after exiting the game would've been more than welcome.

Immunotherapy using checkpoint inhibitors has changed the way we treat several aggressive cancers such as melanoma, non-small cell lung and head & neck cancers, among others, with durable responses achieved in the metastatic setting.

In fact, police established a record number of DUI checkpoints last year, forcing drivers to re-think their after - party plans, and concentrate on before party plans, like arranging a sober driver to take them home.

But working with IBM's Millennial Corps, a community of young employees from around the firm's global offices, the company rolled out a new system called Checkpoint earlier this year.

Fixed an issue where players could get stuck in the pause menus when reloading checkpoints in the campaign.

You make your way between checkpoints known as Sanctuaries and collect a resource similar to souls, called «Salt,» that lets you level up and learn new magic skills.

BMS's drug, ipilimumab (Yervoy), was the first checkpoint inhibitor (a kind of cancer immunotherapy drug that essentially helps the immune system release its brake and go after tumor cells it might normally miss) to get approved in the US in 2011 for melanoma.

When I play video games, I tend to restart certain checkpoints if a segment isn't executed perfectly.

Minit employs multiple checkpoints just like this one throughout the world which are integral to your progress, making it clear to players that each section of the map is its own microcosm of puzzles, narrowing the scope of the game and making it more manageable.

A promising type of immunotherapy, called immune checkpoint therapy, blocks the «off» signal so your body has more time to mount its own defense.

Luckily Lucky has quite a lot of checkpoints so you never have to replay large parts.

Configured, troubleshoot, and upgraded Checkpoint Firewalls for Manage clients, which included network and / or resource access, software, or hardware problems.

Because prescriptions can be a matter of life and death, there are many checkpoints throughout the process during which mistakes can be caught.

Any plan on patching the campaign to save at checkpoints when closing out the game?

Namely, you can't place checkpoints in levels.

The trailer shows off various game modes including Checkpoint racing in Paris and street racing in Chicago, plus a number of customization options and social features.

Milestones are like checkpoints for your business, steps you take to reach your overall goals.

Immune checkpoint blockade therapies use antibodies to counter the defensive tactics of tumor cells.

There are more standard races against opponents this time, but for some reason you're still having to pass checkpoints in order to beat the clock.