Corey's team has three different
chemical classes of drug that all do the same thing - help cells reduce levels of the mutant HD gene.
His team has three different
chemical classes of drug that all do the same thing - help cells reduce levels of the mutant HD gene.
Not exact matches
The new research, published recently as two separate studies in ACS Central Science and the Journal
of the American
Chemical Society, demonstrates that a new
class of drugs called small molecule RNA inhibitors can successfully target and kill specific types
of cancer.
To do so, he sat down with The Merck Index, a standard reference manual for
chemicals,
drugs, and other compounds, and turned to the section on the
class of hormones to which norbolethone's precursor belonged.
For some years now, a new
class of drugs called antibody -
drug conjugates (ADCs) have been used, which work in two ways: they consist
of an antibody that binds selectively to the tumor cell receptor and interrupts the signal to propagate; they also act as a transport vehicle for a
chemical substance that enters the cancer cells with the antibody and triggers their death.
University
of Illinois chemist Martin Burke, a pioneer
of a technique that constructs complex molecules from simple
chemical «building blocks,» led a group that found that thousands
of compounds in a
class of molecules called polyenes — many
of which have great potential as
drugs — can be built simply and economically from a scant one dozen different building blocks.
«Furthermore, they demonstrate that a new
chemical class binds to an alternative site on the enzyme, which overcomes existing
drug resistance and opens up the exciting possibility for development
of a novel
class of anti-TB
drugs.»
A new
class of drugs under development to treat depression has shown some success by targeting brain cells» ability to respond to the
chemical messenger glutamate.
Working with SBP's Conrad Prebys Center for
Chemical Genomics, we are uniquely positioned for the state -
of - art
drug discovery process with world -
class experts in pharmaceutical and biotech
drug discovery.
As a postdoc at Alnylam, he's been looking at how
chemical modifications on a
class of RNAs called small interfering RNAs can make them better
drugs.
The fact that atrazine uses the aromatase pathway to increase estrogen production is important, because it means the
chemical could work directly against aromatase inhibitors, a
class of drugs used to treat breast cancer.