Bacterial cells communicate with one another by using
chemical signal molecules, which they synthesize and secrete into their surroundings.
Autoinducers (
chemical signaling molecules that produce more of themselves inside the cell) control the switch that turns the light genes off and on.
Pheromones are considered to be airborne
chemical signaling molecules that are released by humans, animals, and plants into the environment and they can affect the physiology and or behavior of other members of the same species.
Not exact matches
Mitochondria, specialized organelles found in nearly every cell of the body, use cellular respiration to generate one of the most important sources of
chemical energy — adenosine triphosphate (ATP), a versatile nucleotide that powers everything from cell division to cell
signaling to transportation of large
molecules across the cell membrane.
When the team applied the technique to a sample of the organic
molecule PTCDA, not only did the
molecules show up in intricate detail, an electrical
signal was also detected between them (coloured green below), at exactly the locations where hydrogen bonds are present (Journal of the American
Chemical Society, DOI: 10.1021 / ja104332t).
A study published in the journal PLOS ONE reports that the synthetic
molecule JK - 31 blocks the
signalling of a «growth factor»
chemical that promotes the creation of networks of blood vessels to feed tumors.
Typical blood glucose testing strips also contain a
molecule that ultimately amplifies the
signal from the
chemical reactions on the strip enough to register electronically on a monitoring device.
Frey and his colleagues made use of mathematical models to analyze the complex interplay between ecological factors and population dynamics, and were able to demonstrate that populations can indeed respond in a coordinated fashion to
chemical information even when the
signal molecules are generated by only a subset of the cells.
The authors note that more work must be done, however, because only one of these species engaged in a full cycle of listening and speaking in which the artificial cells sensed the
molecules coming from the bacteria, and the bacteria could perceive the
chemical signal sent in return.
It was originally investigated in 1995 by pharmacologist Franco Borsini and a team of researchers at Boehringer Ingelheim Italia in Milan as an antidepressant because of its ability to regulate neurotransmitters — the brain's
chemical -
signaling molecules.
For the study, the Bohn worked closely with TSRI chemist Thomas Bannister, PhD, to develope new potential drug
molecules; they then tweaked their
chemical structures to systematically vary the «bias» between the two pathways — G protein
signaling and beta - arrestin recruitment.
While the PS is moving across the cell membrane and looking for a stronger
chemical signal, only a few
molecules of the breaking protein Cdc24 are present in the machinery.
Dopamine, a
molecule crucial for
signaling between neurons, can not cross this barrier, which is why its
chemical precursor, L - dopa, is used instead to treat Parkinson's disease.
A
chemical interaction with target
molecules subtly alters the magnetic
signal from the xenon; by detecting this change researchers can identify the
molecules in a complex mixture.
Gangliosides are lipid
molecules that were proposed to play key roles in numerous biological processes, including the formation of raft domains, the entry of toxins into cells and
chemical signal reception.
During the
chemical reaction they studied — the hydrogenation of propylene to propane — parahydrogen is part of the propane
molecule and is converted into observable nuclear magnetism to enhance the MRI
signal.
By looking for unique
chemical signatures in light and radio
signals gathered by telescopes, researchers have observed more than 140
molecules — including increasingly complex organic ones — surrounding stars or in interstellar space.
The excited atoms, in turn, emit
signals that can be used to create images of the brain, muscle, and other tissues, which can be distinguished based on the local physical and
chemical environment of the water
molecules.
These symptoms are the result of the loss of specialized cells in an area of the brain called the substantia nigra pars compacta (SNc) that specialize in producing the
chemical signal -
molecule dopamine and are responsible for turning off excess firing of neurons that control muscles.
These small
molecules exhibit fascinating
chemical diversity and regulate lifespan, reproduction, behavior and many other traits, often through
signaling pathways that are shared throughout the animal kingdom.
By utilizing the tools of cell and molecular biology, he studies the mechanisms by which
chemical (for example, specific cell adhesion
molecules) or mechanical
signals (for example, cyclic strain) are sensed by cells and alter their proliferation and specialization to either promote tissue growth or destruction.
Lycopene can apparently inhibit both inflammatory
chemicals and inflammatory
signalling, possibly by inhibiting the inflammatory master
molecule NF - KappaB.