HAIRS all over the body use the same two
chemical signalling pathways to communicate with each other — a finding that might help treat baldness.
The researchers have some evidence that S. gallolyticus may also work through other
chemical signaling pathways to enhance colon cancer growth.
Not exact matches
The
chemical tells individual neurons to fire off a
signal or not, influencing other brain
signals and
pathways, and essentially serves as a traffic cop of motivation, emotion, and social behavior.
However, if you don't see those [Earth - like]
signals, you can't conclude that there isn't life, because the life may be completely different; it may proceed in some
chemical pathway that we might mistake for nonbiotic processes, for geologic processes.
The group is now pursuing studies that couple the mechanical forces of a blast, or pressure wave, to the activation of
chemical -
signaling pathways in neural cells.
What was especially «exciting» about this finding, he says, is that these variations were near a neural highway that previous studies have shown helps regulate life span in worms and flies, and that stopping
chemical signals from this brain
pathway extends the life span of mice.
For the study, the Bohn worked closely with TSRI chemist Thomas Bannister, PhD, to develope new potential drug molecules; they then tweaked their
chemical structures to systematically vary the «bias» between the two
pathways — G protein
signaling and beta - arrestin recruitment.
«Recently, the attention of scientists has been attracted to endocrine - disrupting
chemicals (EDCs), compounds that are suspected of promoting the development of various metabolic disorders via their capacity to impact hormonal and metabolic
signaling pathways,» said lead author Shane Regnier, a doctoral candidate at the University of Chicago's Committee for Molecular Metabolism & Nutrition.
Cells move along this
pathway partly carried by the flow of cerebrospinal fluid and partly guided by
chemical signals.
Ongoing research focuses on
chemicals that alter Ca2 +
signaling pathways essential physiological processes including neurodevelopment, striated muscle function and oocyte fertilization.
In the brain, cells are among the units, migratory
pathways are the highways or roads, and various electrical or
chemical signals, including dopamine, are the communication systems.
To help things along, the team initiated a
chemical reaction known as the TGF - ß
signaling pathway during the early stages of reprogramming, which further improved reprogramming success rates.
These small molecules exhibit fascinating
chemical diversity and regulate lifespan, reproduction, behavior and many other traits, often through
signaling pathways that are shared throughout the animal kingdom.