These chemicals damage the cells and may distort the results.
Those chemicals damage cells, promote widespread internal (and invisible) inflammation, and lead to a vast number of health concerns now considered common such as cardiovascular disease and cancer.
Not exact matches
It dispatches the hormones and
chemicals that repair
damaged cells and replace dead ones.
@Chad: I. Mutations in DNA sequences generally occur through one of two processes: A. Environmental factors: DNA
damage from environmental agents such as ultraviolet light (sunshine), nuclear radiation or certain
chemicals B. Mistakes that occur when a
cell copies its DNA in preparation for
cell division.
Oxidation is a
chemical reaction that releases free radicals, which proceed to cause
cell damage.
Vitamin E helps protect your
cells against free radicals,
chemicals that oxidize and
damage your proteins,
cell membranes and DNA.
Reactive oxygen species, also called free radicals, are
chemicals that typically contain oxygen, are known to be found in cigarette smoke, and cause DNA
damage in
cells.
These solutions slowly and delicately draw out the antifreeze - like
chemicals without
damaging the
cells.
[Robert Siman et al, Serum SNTF Increases in Concussed Professional Ice Hockey Players and Relates to the Severity of Post Concussion Symptoms] A strong blow to the head causes
chemical changes within nerve
cells that
damage their structural proteins.
All living organisms maintain a reducing environment inside their
cells, all
cells contain complex systems of antioxidants to prevent
chemical damage to the
cells» components by oxidation.
They discovered that the
chemicals and radiation used to kill tumor
cells damage the stem
cell reservoir in the hippocampus and nearly halt the formation of new neurons in both children and adults.
When the researchers exposed mice to radiation and
chemicals that harm DNA,
damaged stem
cells transformed permanently into melanocytes.
Defined as the harnessing of living processes to achieve healing and repair of
damaged and diseased tissues by Tim Hardingham, director of the UK Centre for Tissue Engineering, it is a field that requires collaborative research involving
cell and molecular biologists,
chemical engineers, materials scientists, and surgeons.
Specifically, the Mount Sinai study was designed to test whether pharmacological compounds designed to block the function of XPO1 / CRM1 could stop disease progression in mouse models that exhibit some of the characteristics of MS. Researchers found that two
chemical agents (called KPT - 276 and KPT - 350) prevented XPO1 / CRM1 from shuttling cargo out of the nucleus of nerve
cells, which protected them from free radicals and structural
damage.
If this environment is harmed by
chemicals, such as through
damage to gut
cells, it could impact the health of the organisms and would lead to a number of fish diseases but this technique will enable us to increase the tests we can carry out and improve our understanding of how to preserve gut health.»
By measuring levels of the stress hormone cortisol, plus other
chemical markers, the team found that the task caused more
cell damage in the women who were already stressed.
A few years ago, MS researchers were focused on a new type of immune
cell called the Th - 17
cell, which appeared to be a key player in driving the neuronal
damage in MS. Because Th - 17
cells produce the cytokine IL - 17, researchers likewise thought this
chemical was essential to the disease.
It belongs to a group of
chemicals called reactive oxygen species (ROS), which scientists suspect to have a
damaging effect on
cells and their components.
In a bid to progress beyond the shotgun approach to fighting cancer — blasting malignant
cells with toxic
chemicals or radiation, which kills surrounding healthy
cells in the process — researchers at the Harvard - MIT Division of Health Sciences and Technology (HST) are using nanotechnology to develop seek - and - destroy models to zero in on and dismantle tumors without
damaging nearby normal tissue.
Plaque hinders neuronal activity by gumming up synapses (spaces between
cells through which
chemical or electrical information is transmitted), eventually
damaging nerve
cell branches and leading to neuronal death.
Exactly how the tea protects against heart disease remains unclear, but Kuriyama speculates that antioxidant
chemicals in green tea, called polyphenols, reduce the action of free radicals in the body, which may
damage cells.
Mutations occur, for example, when
cells copy their DNA incorrectly or fail to repair
damage from
chemicals or radiation.
To overcome these issues, Steven J. Jonas, Paul S. Weiss, Xiaobin Xu and colleagues sought to create biocompatible nanospears that can be configured to transport DNA into
cells precisely using an external magnetic field without either
damaging the
cells or having to use
chemical propellants.
Photodynamic therapy (PDT), involves the use of
chemicals called photosensitizers that are activated by exposure to specific wavelengths of light to release reactive molecules that can
damage nearby
cells.
Staining can be a long and exacting process, and the added
chemicals can
damage cells.
Moreover, the scientists observed traces of other
damaging chemicals often recruited by RIPK1 to kill
cells.
Mutagens are
chemicals that can cause DNA
damage in
cells that in turn can cause cancer.
Experiments conducted in mice and in human ALS
cells reveal that when RIPK1 is out of control, it can spark axonal
damage by setting off a
chemical chain reaction that culminates in stripping the protective myelin off of axons and triggering axonal degeneration — the hallmark of ALS.
Research on lab animals has shown some of the
chemicals cause cancerous tumors and
damage developing brain
cells, and some can alter hormones essential to reproductive and neurological development.
These biologically
damaging chemicals can kill the inner ear's hair
cells, the ones that sense sound.
«Energy production can also generate reactive
chemical species — often referred to as «reactive oxygen species» or «oxidants» — as by - products, which can be
damaging to
cells.
The fibers are thought to do so by skewering
cells, setting off
chemical reactions that lead to inflammation, DNA
damage and
cell death.
Cells lining the blood vessels send
chemical signals, called cytokines, to the tumour to help it resist DNA
damage and to recover.
Damage to proteins, which are essential for all the
chemical reactions within the
cell, could also have dire consequences.
Even though
cells are not threatened by hurricanes and earthquakes, the
damage induced by heat or radiation is equally devastating: Important proteins that control
chemical reactions, transport substances or recognize signal substances, among others, lose their structure and are rendered useless.
Another well - known invention is a process called bioorthogonal
chemical reactions, which can be used to label proteins, sugars, and other molecules in living
cells and animals without
damaging the
cells.
That news alone was an exciting breakthrough, but there's more: In lab mice,
damaged retinal ganglion
cells survived longer and were able to regenerate when excess zinc was removed through a
chemical process called chelation.
Without BRCA - induced DNA repair, a molecule called ATM kinase sensed the excessive DNA breaks and activated a
chemical pathway that kills off
damaged cells.
They will also screen for
chemicals that can stop or even reverse the
damage diabetes does to β
cells.
They showed that basal
cells were much more efficient at repairing DNA
damage, allowing them to survive and reproduce following exposure to
chemicals or radiation that
damaged the DNA.
Further studies suggested that
damage to
cells in the barrier triggered a
chemical cascade that affected the neighboring
cells, Case says.
Most mutations are caused by
chemical or radiation
damage from the immediate environment or within the
cell itself.
In that short window, they send
chemical signals that instruct the mouse's own
cells to repair the
damage caused by MS.. This realization could be important for therapy development.
When Lin engineered the telomerase - expressing hepatocytes to die in response to a
chemical signal and gave the mice with a liver -
damaging chemical, he found that those animals in which the telomerase
cells had been killed exhibited much more severe liver scarring than those in which the
cells were functional.
The ultimate goal is to produce pluripotent
cells by purely
chemical means within the body to regenerate
damaged parts and to treat disease.
These treatments target any rapidly dividing
cells (not necessarily just cancer
cells), but normal
cells usually can recover from any
chemical - induced
damage while cancer
cells can not.
Oscar Fernandez - Capetillo, Karolinska Institutet / SciLifeLab, and colleagues, have explored how mammalian
cells might become resistant to
chemical inhibitors of ATR, a molecule involved in sensing DNA
damage.
Chemotherapy utilizes
chemicals that interfere with the
cell division process -
damaging proteins or DNA - so that cancer
cells will commit suicide.
Other genetic diseases include Tay - Sachs disease (
damage to the gene for the enzyme hexosaminidase A leads to an accumulation of a
chemical in the brain that destroys it), sickle
cell anemia (improper coding of the gene that produces hemoglobin), hemophilia (lack of a gene for a blood - clotting factor) and muscular dystrophy (caused by a defective gene on the X chromosome).
«This study is a proof - of - principle that drugs of this
chemical type cause energy stress and lower ATP levels to where it kills LKB1 - deficient
cells without
damaging normal, healthy
cells,» says Shaw, senior author of the study.