Not exact matches
According to one
of his analogies: just as the sequence
of letters on a page is extraneous to the
chemistry of ink and paper, so the sequence
of nucleic acids in the DNA molecule (which, when translated, determines the shape
of an organism and its specific characteristics) is extraneous to the chemical forces operative in the genetic process.
Still is it not possible that the specific sequence
of base - pairs in a DNA molecule is extraneous to the
chemistry which bonds the
nucleic acids to one another?
So we must ask whether
chemistry (or any physical science) can specify the overall sequence
of nucleic acids that determines the kinds and shapes
of organisms existing in the biosphere.
So that has made us look again at the
chemistry of replication and start to explore a wider range
of nucleic acids.
Attendees at the astrobiology meeting in Arizona showcased an assortment
of high - tech devices for next - generation exploration, ranging from microfluidic «life analyzers» and integrated
nucleic acid extractors for studying «Martian metagenomics» to exquisitely sensitive, miniaturized organic
chemistry labs for spotting tantalizing carbon compounds and minerals at microscopic scales.
He won two Nobel Prizes for
chemistry, but we claim him for molecular biology because the methods he developed for sequencing proteins and
nucleic acids provide the basis for much
of what we do today.
Joint winner
of the 1980
chemistry prize with Walter Gilbert for his «contributions concerning the determination
of base sequences in
nucleic acids» and winner
of the 1958
chemistry prize «for his work on the structure
of proteins, especially that
of insulin.»
Winner
of the 1982
chemistry prize «for his development
of crystallographic electron microscopy and his structural elucidation
of biologically important
nucleic acid - protein complexes.»
Mirkin is director
of the research group that invented the
chemistry for conjugating DNA and nanoparticles and a pioneer
of the concept
of programmable colloidal crystallization with
nucleic acids.
So that made us look again at the
chemistry of replication and start to explore a wider range
of nucleic acids.
Roger Williams, Burke's postdoctoral advisor in the division
of protein and
nucleic acid chemistry at the Medical Research Council Laboratory
of Molecular Biology, called Burke «simply one
of the best postdoctoral researchers with whom I have worked in the 25 years that I have been a group leader in the Laboratory
of Molecular Biology in Cambridge, UK.