Sentences with word «chemotherapeutic»

Every year, nearly 2,000 people in Switzerland are diagnosed with lymphoma, a disease that can be very aggressive, resisting standard treatments with chemotherapeutic drugs.

The interstitial pressure inside a tumor is often remarkably high compared to normal tissues and is thought to impede the delivery of chemotherapeutic agents as well as decrease the effectiveness of radiation therapy.

Benoit's lab, in the meantime, has been developing polymer nanoparticles as vehicles for delivering chemotherapeutic drugs to specific parts of the body where a disease occurs, in order to minimize damage to healthy tissues.

This is at least suggested by the observation that the mesenchymal subpopulation in the HMLE model remains viable upon most chemotherapeutic treatment regimens, under conditions that allowed the effective elimination of the epithelial population [7].

The fact that four of the drugs used in the tests — heparin, cytochalasin D, ethyl - isopropyl amiloride and choloroquine — are already approved by the Food and Drug Administration for other uses suggests that they may also be useful as chemotherapeutic agents, Nagrath said.

Many chemotherapeutic agents impair the bone marrow's ability to produce cells.

Therefore, combined treatment of low - dose ActD with other chemotherapeutic drugs may be a promising cancer therapy.

We are taking advantage of this ability by using Salmonella to carry or generate effective chemotherapeutic drugs, concentrating them at and throughout the tumor.

In certain types of cancer, erythropoietin production by the kidneys, as well as its activity on the bone marrow, is inhibited by cancer - produced cytokines (the substances that mediate inflammation) as well as by chemotherapeutic drugs.

However, the specificity of conventional chemotherapeutic drugs towards cancer cells is limited.

And chemotherapy is not very effective because most chemotherapeutic agents don't pass out of the bloodstream into the brain.»

After that, new swelling was detected in the lymph nodes, and Dr. Creasey recommended that Andy take Guinness to see Dr. Craig Clifford of the Oncology Service at HOPE Veterinary Specialists, as Dr. Clifford is involved in several ongoing clinical trials with new chemotherapeutics for dogs.

By interfering with the ability of tumors to resist chemotherapeutic medications, anthocyanins can help them work better.

Many pet owners who can not afford or choose not to use full chemotherapeutic protocols, will often receive oral Prednisone only for their pets.

Chemotherapeutic Dose Scheduling Based on Tumor Growth Rates Provides a Case for Low - Dose Metronomic High - Entropy Therapies, Cancer Research (2017).

Valproate increases pro-apoptotic efficacy of chemotherapeutic regimen in small cell lung cancer.

«What we're doing is trying to design chemotherapeutic schedules to better overcome some of the known problems associated with chemotherapy,» said Newton, professor of aerospace and mechanical engineering, mathematics and medicine — the latter at the Norris Comprehensive Cancer Center at the Keck School of Medicine of USC.

Each factor involved in the tumor response — whether it is the speed with which chemotherapeutic drugs reach the tissue or the degree to which cells signal each other to grow — is characterized by a mathematical equation that captures its essence.

The established method of treatment is the use of a combination of various chemotherapeutic agents.

Banerjee S, Wang Z, Kong D et al. 3,3» - Diindolylmethane enhances chemosensitivity of multiple chemotherapeutic agents in pancreatic cancer.

No targeted therapy has been approved for noninflammatory and inflammatory triple - negative breast cancer tumors, and the standard of therapy for these tumors is a combination of conventional cytotoxic chemotherapeutic agents.

Recent studies have suggested that treating patients with low doses of chemotherapy drugs at more frequent, even daily, intervals may be more effective than traditional chemotherapeutic approaches.

Medical advances sometimes originate in veterinary medicine and move to human medicine: chemotherapeutic approaches to osteosarcoma that have proven effective in naturally occurring cancers of dogs treated at our hospital are beginning trials in people with cancer.

The most common chemotherapeutic cocktail is Adriamycin and Cytoxan.

Innate or acquired resistance to current standard - of - care therapies is a major hindrance to successful chemotherapeutic intervention.

BMH - 21 also appears to overcome the tendency of cancer cells to resist chemotherapeutic agents because it finds and targets proteins and shuts down the communication pathways that cells use to continue dividing.

Therapy centers on immunosuppressive doses of steroids and sometimes the use of additional chemotherapeutic agents.

For these patients, there are several chemotherapeutic options; however, each has shown only marginal benefit.

Astrocytes upregulate survival proteins in cancer cells which protect those cells against chemotherapeutic agents such as temozolamide.

«Once chemists got over the excitement of being able to make anything, their attention turned to making functional molecules, and for me, the most interesting molecules are those with pharmaceutical or chemotherapeutic potential, particularly those that act on cancers.

One of these problems, which has become a focus of their research, is chemotherapeutic resistance by competitive release.

Internal Medicine services welcome oncology consultations and can provide chemotherapeutic services.

The findings, published June 22, 2017, in PLoS Genetics, suggest that ribosomal DNA copy number could be used to predict which cancers will be sensitive to DNA - damaging chemotherapeutics.

Many chemotherapeutics act by damaging the DNA.

Rehemtulla adds that if other FDA - approved chemotherapeutic agents reach their targets as successfully as Photofrin did, «then we will have developed a way to make cancer drugs more «tumor - specific,» because they will only get into tumor vasculature and not normal vasculature.

A new drug delivery system for treating lung cancer allow chemotherapeutic drugs to be inhaled, thereby delivering the drug where it is needed while reducing the harmful effects to other organs.

Scientists also eventually determined that the polyphenolic compound is an antioxidant and has chemotherapeutic activity.

Targeting Glioma Stem - Cell Derived Pericytes Disrupts the Blood - Tumor Barrier to Improve Drug Delivery and Chemotherapeutic Efficacy.

But MDR1 is only known to transport chemotherapeutic drugs out of tumor cells, so why would it be expressed in immune cells in the gut?

The team also demonstrated that their DNA - logic devices could activate a non-toxic cancer prodrug, 5 - fluorocytosine, into its toxic chemotherapeutic form, 5 - fluorouracil.

His research on attaching selenium to the leading clinical chemotherapeutic monoclonal antibody for a type of breast cancer shows it can more effectively kill the cancer cells, he reports.

However, those particles also ferried a standard chemotherapeutic toxin to help kill the cancer cells.