Not exact matches
Previous results from the trial have already changed clinical practice — data released last year has led to
docetaxel chemotherapy now being part of the standard of care for many men
with prostate cancer.
A large trial showing that men
with newly diagnosed, advanced prostate cancer lived ten months longer, on average, when they received
docetaxel chemotherapy along
with standard hormone therapy
Patients were randomised 1:1 to receive therapy
with ceritinib or
chemotherapy (pemetrexed or
docetaxel).
The trial actually enrolled 938 patients
with recurrent advanced NSCLC; physicians initially chose pemetrexed or
docetaxel for patients, after which patients were randomized to either
chemotherapy alone or in addition to a cetuximab regimen.
Pertuzumab was approved by the FDA in 2012 for first - line treatment of HER2 + metastatic breast cancer in combination
with trastuzumab and the
chemotherapy docetaxel (Taxotere).