The study found that later COPD risk could be minimised if immunisation was encouraged, if mothers did not smoke and if their children did not smoke when they got older, especially if they had smoking parents or low
childhood lung function.
As a result, the authors say that it will be important to reduce parental smoking, encourage immunisation, and avoid smoking to promote healthy lung function pathways and minimise COPD risk, especially for people who had low
childhood lung function or whose parents smoked.
Not exact matches
Three - quarters of chronic obstructive pulmonary disease (COPD) cases have their origins in poor
lung function pathways beginning in
childhood.
A second study in the journal also suggests that there could be a window of opportunity during
childhood to reduce the risk of poor
lung function in later life.
Importantly, maternal smoking and
childhood asthma not only adversely affected early
lung function, but predisposed children to more rapid
lung function decline if they still suffered from asthma or actively smoked as adults.»
«Persistent
childhood asthma linked to COPD: Study finds that early
lung function predicts
lung growth later in life.»
«Thus, every effort should be undertaken to achieve normal growth of
lung function including non-smoking during teenage years, treatment of asthma in
childhood and reducing exposure to agents such as passive smoking,» Professor Peter Lange concludes.
For the first time, the scientists could quantitate two major trajectories of
lung function leading to COPD: the fast decline trajectory, where
lung function declines very rapidly from a normal level, and the alternative trajectory where suboptimal development of
lung function during
childhood and adolescence is the major determinant of COPD in older age.
The present study shows that the maximally achieved level of
lung function in
childhood and early adulthood is an important determinant of future COPD risk.
Lung function in childhood is most likely related with lung function in adulthood.&ra
Lung function in
childhood is most likely related with
lung function in adulthood.&ra
lung function in adulthood.»
The «early low, accelerated growth, normal decline» path also suggested a somewhat surprising pathway, where some children with low
lung function in
childhood still had an opportunity to grow out of it.
early low, accelerated growth, normal decline (new)-- those with low
lung function in early
childhood followed by a catch - up growth during adolescence and remain normal in adulthood;
It involved a range of university departments and hospitals across Australia and pinpointed six
lung function pathways from
childhood to middle age.
«Maternal smoking in pregnancy may set children with asthma on a trajectory of poor
lung function in later
childhood, and other studies suggest this effect may be lifelong,» Whittaker Brown said in a journal news release.
These findings are also in line with other studies that have shown that chronic caregiver stress in the postpartum and early
childhood period has been associated with persistent wheeze in early
childhood4 as well as factors that may initiate or potentiate inflammation in the
lung (eg, IgE expression, enhanced nonspecific and allergen - specific lymphocyte proliferation, differential cytokine expression).5, 7 Both persistent wheeze and atopy have been linked to reduced
lung function in
childhood.49 This cumulative stress model is particularly relevant given that maternal IPV may become a more direct stressor for toddlers who are witnessing violence against their mothers.50