Sentences with phrase «chimeric hiv»
The work stems from an earlier collaboration between Potash and David J. Volsky (also from Columbia University); they established a chimeric HIV clone with a genetic modification that allows the virus to propagate in rodents instead of humans.
https://www.sciencedaily.com/
In their latest study, Potash and colleagues describe the efficient and reproducible transmission of chimeric HIV from infected male mice to uninfected females via mating, providing the first report of HIV transmission by coitus in an animal model.
Not exact matches
Through gene therapy, researchers engineered blood - forming stem cells (hematopoietic stem / progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV - infected cells.
The SHIV - 89.6 3» construct encodes the HIV - 1 portions of the chimeric virus, cloned into the pBluescript II KS (+) vector (Stratagene).
Preintegration HIV - 1 inhibition by a combination lentiviral vector containing a chimeric TRIM5 alpha protein, a CCR5 shRNA, and a TAR decoy.
Expression of Chimeric Receptor CD4zeta by Natural Killer Cells Derived from Human Pluripotent Stem Cells Improves In Vitro Activity but Does Not Enhance Suppression of HIV Infection In Vivo.
They now show that engineering hESC - and iPSC - derived NK cells with a specific HIV CD4ζ chimeric receptor enhances the suppression of HIV replication in vitro and study these cells in a mouse xenograft model [6].