Balb / c third - party allografts were acutely rejected in
chimeric animals, as were control MRL allografts in non-
chimeric animals.
These results allow us to conclude that failure to detect donor cells in peripheral blood of previously
chimeric animals may not truly reflect the immunological status of these animals.
In addition, mixed lymphocyte cultures using the cells of
the chimeric animals as responder cells to donor splenocytes failed to demonstrate any sensitization or clonal deletion of alloreactive T cells; i.e. T cell responses were identical to those of control animals (n = 4)(data not shown).
Although the T cells of
chimeric animals responded to alloantigen, the response was similar to that of non-chimeric control animals, suggesting that these cells did not appear to lead to deletion of alloreactive T cells.
More importantly,
chimeric animals were protected from rejection of donor - type cardiac allografts.
McCain would ban scientists from using donor eggs to create disease - specific stem cell lines or
chimeric animals to see how human stem cells behave during development.
Biologist Stuart Newman of the New York Medical College in Valhalla is trying to get a patent on a «humanzee» —
a chimeric animal made from human and chimpanzee embryos.
Not exact matches
When researchers create «
chimeric» mice by injecting iPS cells into early - stage mouse embryos, the resulting
animals are unusually prone to cancer.
Hybrid, or
chimeric,
animals may eventually grow human organs to be used in transplants.
Some worry that such human cells, when combined with
animal embryos, could develop into brain cells, sperm, or egg cells in the
chimeric offspring.
In their latest study, Potash and colleagues describe the efficient and reproducible transmission of
chimeric HIV from infected male mice to uninfected females via mating, providing the first report of HIV transmission by coitus in an
animal model.
The subjects of his depictions are
chimeric creatures in a state of metamorphosis; combinations of
animals, organic forms, and natural elements inspired by the ecosystem of the place where the artist works.