This article appeared in print under the headline «
Chimp brains miss out on the groovy feature built into ours»
By pairing these results with a look at the primate family tree, the team concluded that sometime in the recent evolution of humans, our brains outpaced
chimp brains.
A new study of elderly
chimp brains finds the characteristic amyloid plaques and neurofibrillary tangles of Alzheimer's disease.
Some scientists aren't persuaded that
the chimp brains really do match those of human Alzheimer's patients.
But it is possible that there is a factor protecting
chimp brains from severe dementia.
When they measured the concentrations in the same area in
chimp brains, the team found that the differences between chimps and normal humans were much greater for those nine than for the 12 metabolites not implicated in schizophrenia, suggesting that energy pathways implicated in schizophrenia were also altered by human evolution, the team reports this week in Genome Biology.
Raghanti says that the researchers are now counting the neurons in
the chimp brains they studied to determine whether the cells are lost with age, and studying inflammation in the brains.
THEY may not be able to talk, but
chimp brains could have the rudimentary wiring to evolve language.
The strength of the paper, he says, is that the large number of animals involved provide a good sample of the different ways in which
chimp brains age.
But as it turns out,
the chimp brain and the human brain differ hardly at all in their genetic underpinnings.
But after 22 weeks,
chimp brain growth levels off while human development continues.
The finding shows that this population of cells in the human brain is more similar to that of a macaque than
a chimp brain.
Besides the obvious size difference — the human brain is about three times larger than
the chimp brain — little has been known about how the human brain and the rest of the nervous system changed in our lineage over evolutionary time.
550 cc is actually above the maximum
chimp brain size of about 500 cc, and it is by no means typical of habilis.
«These enhancers most likely regulate the same genes in human brain development and
chimp brain development,» explained Ahituv.
Not exact matches
The frontal
brain grooves on a H. naledi endocast, like those in modern humans, lie farther back than the grooves seen in the
chimp MRI scan, Hurst contends.
Endocast researchers need to study the range of
brain surface characteristics in a larger sample of living
chimps and other apes to make more accurate comparisons, Falk says.
MRIs of eight living
chimps reveal substantial variability in the shape and location of certain features on the
brain surface.
BRAINY
CHIMPS Some modern chimps have brain surface features that were thought to have signaled humanlike brain evolution in hominids from as early as 3 million years ago, scans su
CHIMPS Some modern
chimps have brain surface features that were thought to have signaled humanlike brain evolution in hominids from as early as 3 million years ago, scans su
chimps have
brain surface features that were thought to have signaled humanlike
brain evolution in hominids from as early as 3 million years ago, scans suggest.
«If
chimps with their small
brain size can conceptually deal with fire, then maybe we should rethink some of the earliest evidence for fire usage,» Pruetz says.
According to the social theory of intelligence articulated by N. K. Humphrey and Jane Goodall, complex
brains blossom in complex social settings;
chimps and dolphins have to be smart to read the intentions of other
chimps and dolphins.
Humans were thought to be the only primates with
brains that can contain plaques and tangles simultaneously — although one study did find both markers in a single
chimp brain2.
Because the protein is normally found outside of blood vessels in the human
brain, this suggests that plaques may form in a different way in
chimps.
The researchers were not able to link the biological changes in the
chimps»
brains to shifts in their behaviour later in life.
Only 10 % to 15 % of humans are left - handed, compared with one - third of Yerkes
chimps and even more of those in the wild — which suggests that there is very little specialization between the two hemispheres of the
brain in
chimps compared with humans.
For example, you'd think that the primate with the next biggest
brain relative to body would be a close relative — a
chimp or a gorilla.
Whether
chimps actually succumb to Alzheimer's or are immune from symptoms despite having the key
brain abnormalities is not clear.
Although Lucy had a
brain and body the size of a large
chimp — and probably slept in a tree nest — she walked fully upright and her species may already have lost its agility in trees as it adapted to life on the ground.
But thanks to a newly founded center that collects
brains from
chimps that die at zoos or research centers, the team was able to examine the
brains of 20
chimps aged 37 to 62 — the oldest recorded age for a
chimp, roughly equivalent to a human at the age of 120.
Matsuzawa told the Associated Press that he thinks the
chimps had the edge, because they were younger and, also, human ancestors lost much of this skill over time to free
brain space for language ability.
In 2008, Walker led a team that found both plaques and tangles in a study of a single, 41 - year - old
chimp that died from stroke, although that
chimp's distribution of plaques and tangles didn't resemble those in human
brains with Alzheimer's.
Raghanti says that the 20
chimps whose
brains she studied had not been tested for cognitive or behavioral changes.
In both
chimps and humans, this
brain region continues to grow and organize for years after birth, allowing us to learn and develop socially.
New work on primates bolsters the idea that diet — rather than social complexity — was key to evolution of our big
brains, says
chimp expert Richard Wrangham
58 Why We Are Not
Chimps Humans and chimpanzees are about 98 percent alike, yet the human
brain is three times bigger and far more complex...
The letter further contends that recent
chimp studies for the first time have identified «unique features of the human
brain and have documented the unusual vulnerability of humans to a variety of disorders, including Alzheimer's disease, infectious diseases, cancer, and heart disease.»
This means that
chimps have greater limitations on the ways in which their
brains can develop and on their capacity to learn new behaviors or skills compared with humans.
A multitude of factors help makes the human
brain superior to the
chimps», but new research indicates that looser genetic control of
brain development in humans allows us to learn and adapt to our environment with more flexibility than our primate cousins.
Once the human and
chimp genomes were deciphered about a decade ago, they realized they could now begin to pinpoint the molecular underpinnings of our big
brain, bipedalism, varied diet, and other traits that have made our species so successful.
He and Duke graduate student Lomax Boyd scanned the genomic databases and combed the scientific literature for enhancers that were different between humans and
chimps and that were near genes that play a role in the
brain.
Stop a couple of rounds short of that and, at about one - third the size of a human
brain, you've got one for a
chimp.
Still,
chimps and humans have very different
brains.
As a result, the embryos carrying human HARE5 have
brains that are 12 % larger than the
brains of mice carrying the
chimp version of the enhancer.
Given the outward differences, it seems reasonable to expect to find fundamental differences in the portions of the genome that determine
chimp and human
brains — reasonable, at least, to a brainocentric neurobiologist like me.
The blue stains in these developing mice embryos show that the human DNA inserted into the rodents turns on sooner and is more widespread (right) than the
chimp version of the same DNA, promoting a bigger
brain.
These hominids, whose remains date to between about 100,000 and 60,000 years ago (SN: 4/30/16, p. 7), had
chimp - sized
brains, short statures and, like H. naledi, some skull features resembling early Homo species.
They also have
brains that are 20 percent smaller than those of
chimps.»
Then for HARE5, the most active enhancer in an area of the
brain called the cortex, they made minigenes containing either the
chimp or human version of the enhancer linked to a «reporter» gene that caused the developing mouse embryo to turn blue wherever the enhancer turned the gene on.
The hybrid of familiar face and tiny
brain means Toumaï probably lived just after the time when
chimps and hominids were going their separate ways.
One way to discern their function: Breed
chimps that carry a uniquely human stretch of DNA and see what happens to their
brains.