This includes utilizing a modified
chimpanzee virus as a vaccine carrier to induce an immune response against HIV, and a new therapeutic vaccine against human papillomavirus (HPV), a leading cause of cervical cancer.
Garry argues that, at that rate of change, it would have taken hundreds of years for the closest equivalent
chimpanzee virus to become HIV.
HIV may have been associated with humans for hundreds of years rather than recently evolving from
a chimpanzee virus, says a virologist from New Orleans after analysing tissue from a young male prostitute who died 30 years ago.
Of the three strains of HIV known to infect humans, we know that two — the one causing the global AIDS epidemic and another that has infected a small number of people in Cameroon — came from
a chimpanzee virus called SIV.
The chimpanzee virus could be used to make vaccines to various pathogens, including hepatitis, human papillomavirus, and HIV.
A chimpanzee virus could provide a useful alternative for vaccine development, according to new research in mice.
Not exact matches
Hunting and deforestation have already brought
chimpanzees to the brink of extinction, but «diseases such as anthrax, Ebola, or introduced human respiratory
viruses may serve as the final nail in their coffin,» says disease ecologist Tom Gillespie of Emory University in Atlanta.
The deaths of five Ugandan
chimpanzees have been traced to a human cold
virus, and DNA tests suggest all African chimps are vulnerable
The
virus kills several species, including antelopes,
chimpanzees, and gorillas.
Researchers have identified the evolutionary origins of human herpes simplex
virus (HSV)-1 and -2, reporting that the former infected hominids before their evolutionary split from
chimpanzees 6 million years ago while the latter jumped from ancient
chimpanzees to ancestors of modern humans — Homo erectus — approximately 1.6 million years ago.
Researchers at the University of California, San Diego School of Medicine have identified the evolutionary origins of human herpes simplex
virus (HSV)-1 and -2, reporting that the former infected hominids before their evolutionary split from
chimpanzees 6 million years ago while the latter jumped from ancient
chimpanzees to ancestors of modern humans — Homo erectus — approximately 1.6 million years ago.
The viral family tree showed that HSV - 2 was far more genetically similar to the herpes
virus found in
chimpanzees.
In 1997 Charles M. Rice, now head of the laboratory of virology and infectious disease at the Rockefeller University, showed that mutating the viral protease in hepatitis C — infected
chimpanzees stopped the
virus, the first clue about the enzyme's importance.
Chimpanzees are popular subjects for AIDS research (even though their immune system rarely succumbs to the
virus) and are used in painful cancer and psychological tests, as well as for research on blood diseases and organ transplants.
Recent research suggests the
virus «jumped» to humans from a West African subspecies of
chimpanzee (Pan troglodytes troglodytes) intermittently decades or even centuries ago.
Researchers have long suspected that
chimpanzees were the source of HIV - 1, the AIDS
virus, but proof from the wild was missing.
As if poaching, logging, habitat loss and climate change aren't bad enough, wild
chimpanzees now face a new, deadly peril: a
virus that causes common colds in people.
Researchers believe that sometime in the 1930s a form of simian immunodeficiency
virus (SIV) jumped to humans who butchered or ate
chimpanzee bush meat in the Democratic Republic of Congo.
The ebola
virus is responsible for thousands of gorilla and
chimpanzee deaths in Africa and the origin of HIV, the
virus which causes AIDs, is SIV, simian immunodeficiency
virus.
So Emerman and colleagues resurrected the analogous protein from PtERV1, based on its remnants in
chimpanzees, and inserted it into a defective version of the mouse
virus, which could infect cells but not reproduce.
The vaccine that has been tested in the United States was made from a cold - causing
chimpanzee adenovirus that had been engineered to express proteins from two species of the Ebola
virus, known as Zaire and Sudan (after their origins), and that was already available when the trial began in early September.
It uses
chimpanzees in an effort to understand protective immunity to the hepatitis C
virus.
When Peter Parham's postdoc first showed him data suggesting a gene in some wild
chimpanzees infected with the AIDS
virus closely resembled one that protects humans from HIV, he was skeptical.
Gorillas aren't the only victims; Bermejo estimates that the
virus may have wiped out more than80 percent of the local
chimpanzees too.
The
virus most closely related to HIV - 1 is a simian immunodeficiency
virus (SIV) thus far identified only in captive members of the
chimpanzee subspecies Pan troglodytes troglodytes.
Tantalisingly, the stowaway
virus might even provide clues to what makes us different from
chimpanzees and other non-human primates.
Over the past 20 years, evidence has accumulated that points to Africa and a similar
virus in
chimpanzees.
That study similarly analyzed fecal samples and isolated an AIDS - like
virus, called SIVcpz, from 16
chimpanzees.
Although outbreaks are rare, Ebola
virus, Marburg
virus, and other so - called filoviruses periodically cause massive hemorrhaging in humans,
chimpanzees, gorillas, and other primates.
The
virus originated from another unidentified species of hominin that in turn got it from
chimpanzees.
Mouse, Rat, Sheep, Cow, Human, Xenopus laevis, Monkey, African green monkey, Chinese hamster, Drosophila C
virus (predicted:
Chimpanzee, Zebrafish)
Humans and
chimpanzees, for instance, have slightly different versions of the hepatitis B
virus, both of which likely mutated from a version that infected their shared ancestor more than four million years ago.
New research uses innovative data modelling to predict which species acted as an intermediary between our ancestors and those of
chimpanzees to carry HSV2 — the genital herpes
virus — across the species barrier.
Chimpanzees living in Africa, where scientists believe a chimp first passed the
virus that became HIV on to a person.
Scientists found clues to suggest this happened with HIV after detecting a very similar
virus in monkeys and in
chimpanzees and other great apes.
This spectacular sci - fi adventure begins when a failed experiment gives a baby
chimpanzee human - like intelligence, but also creates a
virus that nearly destroys mankind.
Since
chimpanzees are significantly stronger than humans, once an army of them gets a hold of guns, the few remaining humans who have not succumbed to the
virus don't stand a chance.
Director Danny Boyle Cast Cillian Murphy, Naomie Harris, Brendan Gleeson This town is coming like a ghost town The first scene in Danny Boyle's symbolic UK - set zombie fest is hairy in more ways than one: a group of animal activists descend on a biological vivisection centre and release a
chimpanzee infected with rage, a contagious rabies - like
virus.
While these simian
viruses crossed over to human populations almost certainly as a result of humans ingesting
chimpanzee flesh, directly transplanting the organs of other species into humans is also vector for viral transmission.
And although the origin of HIV - 1 remains uncertain,
viruses related to HIV - 1 have been isolated from the common
chimpanzee (Pan troglodytes), as well as two African
chimpanzee subspecies (the central P. t. troglodytes and the eastern P. t. schweinfurthii).