In a 1970s University of Maryland
cholera study, this man needed 26 liters of intravenous electrolytes to replace lost fluids.
The cholera studies led to the scuttling of a leading vaccine candidate, a finer understanding of effective immune responses, and, ultimately, compelling evidence that a different cholera vaccine worked.
Not exact matches
Satellite imagery is used for all sorts of climate
study, from identifying conditions that allow infectious diseases like West Nile virus and
cholera to emerge, to creating models for predicting hurricanes, to distinguishing natural resources such as wind, water and sunlight.
A new
study delineates a sequential pattern of changes in the intestinal microbial population of patients recovering from
cholera in Bangladesh, findings that may point to ways of speeding recovery from the dangerous diarrheal disease.
«Also by
studying how the gut microbiota usually recover after
cholera, we gain new ideas about how to manage severely disturbed microbial communities, ideas that can be used to protect against diseases that often follow such disturbance, such as infections that commonly follow antibiotic use.»
King said the city makes a good case
study, since
cholera originated in the region.
The team
studied genetic data from over 1200
cholera samples, some dating back to the 1950s.
Studies have shown shifts in
cholera transmission with recent climate variability.
«As long as there are sufficient nucleic acids preserved in the specimen, there is really no limit,» says Alison Devault, a researcher at McMaster University
studying ancient
cholera.
The results of two
studies, published in Science, present a new «rule - book» to estimate the risk of different
cholera strains causing an epidemic.
«The phages clearly have gained the upper hand, and
studying how they do it can eventually open the door for treating
cholera with phages.»
One
study in the Journal conducted by researchers at the CDC finds that even relatively modest improvements — such as providing more latrines and community water pipes and disinfecting water with chlorine — could over the next two decades prevent up to 78,567 cases of
cholera.
The
study notes that by adding the oral
cholera vaccine (OCV) to the picture — and achieving a 20 percent coverage rate within five years — the number of cases averted could rise to 88,974.
He
studied two types of disease - causing bacteria, Vibrio
cholerae — the infectious agent behind
cholera — and Staphylococcus aureus, which can cause various infections such as abscesses and hospital infections.
Epidemiological and DNA
studies have shown that the outbreak was caused by the «El Tor» strain of Vibrio
cholerae bacteria probably carried by Nepalese peacekeepers.
From
cholera to bird flu, researchers are
studying how diseases spread at such events, in the hopes of preventing a future pandemic.
«During the past three years of armed conflict, Yemenis have been continuously exposed to serious harm and trauma, including air strikes, threats and attacks from armed groups, forced disappearances, torture, a
cholera epidemic, and food and job insecurity,» said Farea Al - Muslimi, a prominent Yemeni scholar and chairman of the Sana'a Center for Strategic
Studies.
Forty years ago Levine was one of a tiny cadre of researchers doing so - called human challenge
studies — intentionally infecting people with V.
cholerae and other pathogens to test drugs and vaccines.
Clinical
studies to combat viral infections, a new diabetes medication, and insights to
cholera are among the many breakthroughs that got their start at scientific and technical conferences, AAAS has reported.
She uses
cholera, responsible for seven pandemics in the past two centuries, as a case
study.
A
study published in PLOS NTDs examining the immune response to one of them in Haitian adults finds that while the first vaccine round elicits a strong
cholera - specific response in the mucosa (the first point of contact with the
cholera pathogen), the booster dose after 2 weeks does not appear to stimulate the immune system further.
Jason Harris, from Massachusetts General Hospital in Boston, USA, and colleagues are
studying a bivalent whole cell oral (BivWC)
cholera vaccine produced in India that received pre-approval by WHO in 2011.
Given similar results from
studies of a different oral
cholera vaccine in Asia, the researchers argue that «additional evaluation of the optimal dosing schedule for oral
cholera vaccines with the goal of improving long - term immunity is warranted.»
The results of two
studies, published in Science (10 November), present a new «rule - book» to estimate the risk of different
cholera strains causing an epidemic.
Researchers from across the world have
studied cholera outbreaks in Africa, Latin America and the Caribbean from the last 60 years
Thus several
studies have used Pseudomonas aeruginosa, Salmonella typhimurium, Staphylococcus aureus or Vibrio
cholera to look at insects as models for mammalian infection [10]--[15].
Here, we
study the origins of biofilm genetic structure by combining model development, numerical simulations, and microfluidic experiments using the human pathogen Vibrio
cholerae.
Jill was the co-founder of Agrosalud, a non-profit health care program in rural Guatemala and collaborated with the University of Miami Field Epidemiology Survey Team on projects in the San Blas archipelago in Panamá, including
cholera intervention, scabies and head lice
studies.
Other aspects of global warming's broad footprint on the world's ecosystems include changes in the abundance of more than 80 percent of the thousands of species included in population
studies; major poleward shifts in living ranges as warm regions become hot, and cold regions become warmer; major increases (in the south) and decreases (in the north) of the abundance of plankton, which forms the critical base of the ocean's food chain; the transformation of previously innocuous insect species like the Aspen leaf miner into pests that have damaged millions of acres of forest; and an increase in the range and abundance of human pathogens like the
cholera - causing bacteria Vibrio, the mosquito - borne dengue virus, and the ticks that carry Lyme disease - causing bacteria.
We believe that the proposal would have been stronger if the PI had forged some institutional ties, or had proposed to collaborate with the local sanitarian community and to integrate this project into a broader effort to
study and control
cholera.