Sentences with phrase «cholesterol drug for»

May 1 Regeneron Pharmaceuticals and Sanofi will cut the net price of their expensive cholesterol drug for Express Scripts customers in exchange for greater patient access, with some savings to be shared with consumers, the companies said on Tuesday.

Regeneron Pharmaceuticals Inc and Sanofi SA will slash the price of their expensive cholesterol drug for Express Scripts Holdings Co customers in exchange for greater patient access, with some savings to be shared with consumers, the companies said on Tuesday.

May 1 (Reuters)- Regeneron Pharmaceuticals Inc and Sanofi SA will slash the price of their expensive cholesterol drug for Express Scripts Holdings Co customers in exchange for greater patient access, with some savings to be shared with consumers, the companies said on Tuesday.

May 1 - Regeneron Pharmaceuticals and Sanofi will cut the net price of their expensive cholesterol drug for Express Scripts customers in exchange for greater patient access, with some savings to be shared with consumers, the companies said on Tuesday.

Not exact matches

The ongoing American Heart Association (AHA) meeting in New Orleans is producing a deluge of data — including some promising prospects for a class of next - generation cholesterol drugs that have been slow to take off so far in the U.S. So - called PCSK9 inhibitors have shown tremendous efficacy in lowering LDL - C, or «bad» cholesterol.

Nor can every product be built for prices the average Joe is willing to risk (for example, the next Tesla automobile), or be brought to market for less than $ 10 million (e.g., the next generation of cholesterol drugs).

PCSK9 inhibitors, the main ingredients in Amgen's Repatha and Sanofi and Regeneron's Praluent treatments, were first approved by the Food and Drug Administration in July 2015 for use by patients with a family history of high cholesterol or those who suffered high - cholesterol - induced heart attacks.

While most of the attention on pharmaceutical prices has been on new drugs for diseases like cancer, hepatitis C and high cholesterol, there is also growing concern about huge price increases on older drugs, some of them generic, that have long been mainstays of treatment.

Recently, the patents on a slew of blockbuster drugs — like Lipitor, which fights cholesterol, and Plavix, which prevents blood clots — have expired, paving the way for less expensive versions.

The food is horrid and leads to why our TV commercial breaks in the US are OVERLOADED with drug ads many of them for GI and cholesterol problems.

@rpratz: How is paying for contraceptive pills different from paying from statin drugs to keep cholesterol levels down?

A doctor of naturopathic medicine and a chiropractor, Dr. King found that his patients with high cholesterol who were not being aided by the drugs for that condition were helped by making bison their primary red meat source.

Sadly, most of us, being on statin drugs for high cholesterol, aren't allowed to eat grapefruit at all, and now it looks like ALL citrus fruit is suspicious for us.

The other drugs are antibiotics to control rosacea, a common skin problem, and a statin for elevated blood cholesterol and lipids

«Putting the genetic and drug study findings together suggests pretty strongly to me that we've been barking up the wrong tree with the HDL cholesterol story for the last 30 years.»

Although tau imaging is still in its earliest stages, Ryan hopes that such imaging will accelerate drug development and that finding a blood - based biomarker for Alzheimer's to reveal risk (much like cholesterol serves as a marker for cardiovascular risk) will change the field dramatically in terms of how doctors can diagnose the disease.

Statins and other drugs are already widely used to lower LDL cholesterol, but there are fewer options for lowering triglycerides.

And «side effects become a big issue» for otherwise healthy people who may take cholesterol - lowering drugs for decades, says Vincent Giguère, a molecular biologist at McGill University Health Centre in Montreal.

Dr. Criner cautioned, however, that the finding that the statin drug has no benefit for prevention of COPD exacerbations does not mean that COPD patients should stop taking statins prescribed for cholesterol lowering or other cardiovascular indications.

Their discovery of the LDL receptor and their efforts to understand how the protein functioned are credited with laying the foundation for the development of the blockbuster class of cholesterol - lowering statin drugs.

A drug approved by the Food and Drug Administration (FDA) for melanoma in combination with a common cholesterol - lowering drug may show promise in controlling cancer growth in patients with non-small cell lung cancer (NSCLC), according to new research from the Icahn School of Medicine at Mount Sidrug approved by the Food and Drug Administration (FDA) for melanoma in combination with a common cholesterol - lowering drug may show promise in controlling cancer growth in patients with non-small cell lung cancer (NSCLC), according to new research from the Icahn School of Medicine at Mount SiDrug Administration (FDA) for melanoma in combination with a common cholesterol - lowering drug may show promise in controlling cancer growth in patients with non-small cell lung cancer (NSCLC), according to new research from the Icahn School of Medicine at Mount Sidrug may show promise in controlling cancer growth in patients with non-small cell lung cancer (NSCLC), according to new research from the Icahn School of Medicine at Mount Sinai.

Tests of drug effects often rely on short - term surrogate indicators (say, change in cholesterol level), for instance, rather than eventual meaningful outcomes (say, heart attacks).

Your doctor may advise you to take a statin if your cholesterol is slightly elevated, but he or she probably will not tell you that out of 35 people taking the drug for four years, only one person will actually benefit from it in terms of avoiding a coronary event or another bad outcome.

I wonder how many people with slightly elevated cholesterol would feel this rather minimal risk reduction to be worth the cost and the potentially bad side effects of taking this type of drug for the rest of their lives.

For instance, note the NNT of 35 for statins (cholesterol - lowering drugs) in the primary prevention (avoiding a first - time event) of any bad thing (such as a heart attack), according to a table provided by the journal Bandolier, found at http://tinyurl.com/mrxnFor instance, note the NNT of 35 for statins (cholesterol - lowering drugs) in the primary prevention (avoiding a first - time event) of any bad thing (such as a heart attack), according to a table provided by the journal Bandolier, found at http://tinyurl.com/mrxnfor statins (cholesterol - lowering drugs) in the primary prevention (avoiding a first - time event) of any bad thing (such as a heart attack), according to a table provided by the journal Bandolier, found at http://tinyurl.com/mrxngz.

The report indicates that Sestrin 3 plays a critical role in regulating molecular pathways that control the production of glucose and insulin sensitivity in the liver, making it a logical target for drug development for type 2 diabetes and metabolic syndrome, which can produce increased blood pressure, abnormal cholesterol levels and insulin resistance.

He added that there is a role for other cholesterol - lowering drugs, for example, in patients who suffer side effects from statins.

A new class of biologic drugs came onto the market in Canada last year, and while more effective for treating high - cholesterol, they are also more expensive.

«For the reduction of heart disease and stroke risk, statins remain the most important drug - based strategy by far because of their demonstrated benefit and their good safety profile,» said Lloyd - Jones, who was a member of the task force that rewrote cholesterol treatment guidelines in 2013 for the American College of Cardiology and the American Heart AssociatiFor the reduction of heart disease and stroke risk, statins remain the most important drug - based strategy by far because of their demonstrated benefit and their good safety profile,» said Lloyd - Jones, who was a member of the task force that rewrote cholesterol treatment guidelines in 2013 for the American College of Cardiology and the American Heart Associatifor the American College of Cardiology and the American Heart Association.

Darshak Sanghavi, chief of pediatric cardiology at the University of Massachusetts Medical School in Worcester, notes that although the FDA has approved some statins for use in children with a genetic problem leading to high cholesterol, there are no studies on the drugs» long - term side effects in children.

«It does not bother them in the least to ask their doctors for drugs to lower blood cholesterol while they continue to eat sausages, pâté and cheese,» he says.

But in no other category, except for medication to lower blood cholesterol, is the difference as stark as with the psychotropic drugs.

Results of a phase 2 study published in The Lancet suggest that simvastatin, a cheap cholesterol lowering drug, might be a potential treatment option for the secondary progressive, or chronic, stage of multiple sclerosis (MS), which is currently untreatable.

It also showed that the public cost of expanding public coverage for high - cost drugs — such as treatments for cancer and rheumatoid arthritis — would be modest and, under most plausible scenarios, would be offset by savings achieved in relatively common drug classes — like treatments for high cholesterol and high blood pressure.

Alnylam is testing seven RNAi drugs in the clinic, for conditions ranging from hepatitis B to high cholesterol.

But the big picture is alarming: Patients» online reviews of three over-the-counter drugs — two for lowering cholesterol and one for losing weight — greatly exaggerate how well these substances actually work for most people, says psychologist Mícheál de Barra of the University of Aberdeen in Scotland.

Intriguingly, the study also found that drugs called statins, which are better known for their cholesterol - lowering properties, appeared to alleviate the effects of telomere damage — and may even have protected telomeres against degradation.

People who stop taking cholesterol drugs may be at an increased risk for developing Parkinson's disease, according to research that appears in the July 24, 2013, online issue of Neurology ®, the medical journal of the American Academy of Neurology.

Certain cholesterol levels, for example, have been proven to adequately reflect a patient's risk of having a heart attack, so a drug that reduces those levels may reasonably be presumed to lower cardiovascular mortality.

For instance, pharmaceutical companies will most likely continue to generate more lucrative cures for hypertension and high cholesterol, even though existing drugs work well, and ignore other disorders that lack effective druFor instance, pharmaceutical companies will most likely continue to generate more lucrative cures for hypertension and high cholesterol, even though existing drugs work well, and ignore other disorders that lack effective drufor hypertension and high cholesterol, even though existing drugs work well, and ignore other disorders that lack effective drugs.

Graveline, a former NASA astronaut and flight surgeon, suffered a bizarre episode in 1999 shortly after he was prescribed the popular statin drug Lipitor for his elevated cholesterol.

Pfizer Inc.'s cholesterol - lowering drug torcetrapib, for example, turns off one specific enzyme that allows atherosclerosis, the cause of almost all heart attacks, to progress.»

Suddenly Abramson, who had taken many hits for his critiques of cholesterol - lowering drugs, was joined by physicians calling for more openness in research and more careful examination of the evidence before drugs are put on the market.

Cancer treatments dominate the list, but since 2011 the U.S. Food and Drug Administration has approved new protein - based biologics for the treatment of Lupus, Crohn's disease, rheumatoid arthritis, multiple sclerosis, kidney failure, asthma and high cholesterol.

Thus, PCSK9 is an excellent target for clinical inhibitors that lower blood LDL concentration and therefore cholesterol levels; in fact, two different drugs were approved for this purpose by the US Food and Drug Administration in 2015.

Therefore, PCSK9 is an excellent target for clinical inhibitors that lower blood LDL concentration and therefore cholesterol levels; in fact, two different drugs were approved for this purpose by the US Food and Drug Administration in 2015.

Their work laid the groundwork for drugs called statins that block cholesterol synthesis, increase LDL receptors, lower blood cholesterol and prevent heart attacks.

The project encompasses many drugs commonly prescribed in the primary care setting, including various medications for hypertension and cholesterol.

Since beta - CDs are currently being tested in humans for the treatment of genetic forms of cholesterol accumulation (e.g. Nieman - Pick disease), a successful result in this study might mean that the drug combination could then be accelerated for testing in clinical trials for AMD.

Protein function discoveries in the past 20 years have been the impetus for therapies for cystic fibrosis, and the ability to inhibit certain types of protein expression is at the heart of cholesterol - lowering statin drugs.