Not exact matches
But the big picture is alarming: Patients» online reviews of three over-the-counter
drugs — two for lowering
cholesterol and one for losing weight — greatly exaggerate how well these substances actually
work for most people, says psychologist Mícheál de Barra of the University of Aberdeen in Scotland.
For instance, pharmaceutical companies will most likely continue to generate more lucrative cures for hypertension and high
cholesterol, even though existing
drugs work well, and ignore other disorders that lack effective
drugs.
Their
work laid the groundwork for
drugs called statins that block
cholesterol synthesis, increase LDL receptors, lower blood
cholesterol and prevent heart attacks.
Among the newly funded investigations are: the development of animal models of diabetic eye disease to learn how fenofibrate, a
drug clinically - approved to treat
cholesterol, protects the eye from diabetes - related damage; the development of a specialized camera to capture how the retina's rods and cones (responsible for turning light energy into shapes and colors)
work in health and how they fail in retinal diseases; and the exploration of mechanisms by which intestinal tract bacteria impact the health of the eye.
At the basic level, this
work opened the field of receptor - mediated endocytosis, and at the clinical level it helped lay the conceptual groundwork for development of
drugs called statins that lower blood LDL -
cholesterol and prevent heart attacks.
Kuusisto and Page have received approval to use de-identified electronic health records from the National VA Hospital, with approximately 10 million records, to continue the
drug repurposing
work, examining several
drug effects such as lowering of
cholesterol levels or blood pressure.
«My weight hit 274 pounds on my 5» 7» frame, my joints were aching from the statin
drugs used to lower my
cholesterol, I was winded walking up stairs, and I was taking blood pressure medicine that wasn't
working all that well.
Vytorin lowers LDL
cholesterol by blocking its absorption in the intestines, while other
drugs work in different ways.
Once you start taking a statin or another
cholesterol - lowering
drug, you must continue taking them forever, or switch
drugs if one isn't
working or is causing side effects.
Despite the weak predictive value of Total and LDL
cholesterol, people with elevated numbers are often instructed to lower
cholesterol by any means necessary... including a low - fat diet (which doesn't
work) and statin
drugs.
Statin
drugs work very well at reducing
cholesterol measurements in the blood.
Statin
drugs work by preventing the formation of
cholesterol, and reducing LDL
cholesterol, which is considered the «bad»
cholesterol.
Yet in women, heart disease is strongly associated with artery spasm and clotting issues, and thus far, none of the national studies using
cholesterol medications for women have ever shown that these
drugs work.
Drugs like prednisone
work by stimulating cells throughout the body to give up
cholesterol and other nutrients, and then carrying them to the site of injury.
People should stop drinking, lose weight, take measures to control diabetes, and
work to lower
cholesterol and triglyceride levels, while being aware that many
drugs such as
cholesterol - lowering
drugs can exert toxic effects on the liver cells.
Of course, some of this
work was paid for by
drug companies hoping to capitalize on Alzheimer's with
cholesterol - lowering statin
drugs.
Since 2015 there have been a few pharmaceutical companies
working on a new
cholesterol - lowering
drug type as a replacement for the older class of statin
drugs, such as Lipitor.
The lab he
works with has been credited with discovering a gene responsible for low LDL blood levels, and was responsible for the latest general of
cholesterol lowering
drugs.