Sentences with phrase «cholesterol homeostasis»
"Cholesterol homeostasis" refers to the body's ability to maintain a balanced or stable level of cholesterol in the bloodstream. It involves a delicate balance between the production, absorption, and elimination of cholesterol in the body. Full definition
His seminal research has defined apoE's critical role in cholesterol homeostasis and atherosclerosis.
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Dietary fibre modifications that are low in fat and glucose reduce the risk for AD by not only effecting cell membranes and nutrient sensing G coupled receptors but also by regulating number of nuclear receptors such as histone deacetylases (HDAC) and peroxisome proliferator activated receptors (PPAR) that control glucose, fatty acids and cholesterol and have significant effects on the brain cholesterol homeostasis and amyloidosis.
Recent evidence suggests that inhibitors of PCSK9, a liver enzyme involved in regulating cholesterol homeostasis, could provide an effective alternative or adjunct to statin therapy in high - risk hypercholesterolemic patients.
Proprotein convertase subtilisin / kexin type 9 (PCSK9) is an enzyme that regulates plasma cholesterol homeostasis through its interaction with the LDL receptor (LDLR).
Given annually to post-doctoral fellows who demonstrate original investigation and professional excellence in preparing scientific papers, Dr. Lee won second place in basic science for this publication: «Dysregulation of Cholesterol Homeostasis in Human Prostate Cancer through Loss of ABCA1» Lee BH, Taylor MG, Robinet P, Smith JD, Schweitzer J, Sehayek E, Falzarano SM, Magi - Galluzzi C, Klein EA, and Ting AH Cancer Res 2013 Feb 1; 73 (3): 1211 - 8 PMID: 23233737
Dr. Goldstein and his colleague, Michael S. Brown, discovered the low density lipoprotein (LDL) receptor and worked out how these receptors control cholesterol homeostasis.
by regulating number of nuclear receptors such as histone deacetylases (HDAC) and peroxisome proliferator activated receptors (PPAR) that control glucose, fatty acids and cholesterol and have significant effects on the brain cholesterol homeostasis and amyloidosis.
We are also studying a related liver - specific gene discovered in our lab, the sister of P - glycoprotein (sPgp), and its function in bile formation and cholesterol homeostasis.