Not exact matches
After secretion, apolipoprotein E and
cholesterol associate with high - density lipoprotein to form a
particle that can
deliver cholesterol to the liver by receptor - mediated endocytosis.
The differences between the lipoproteins secreted by astrocytes and those found in the CSF suggest that the astrocytes produce
particles that help the brain rid itself of excess
cholesterol in addition to helping
deliver membrane components to the nerve cells.
It seems fairly clear that those on keto and very - low - carb diets who get most of their energy from fat — including their own fat stores — tend to have more LDL
particles circulating in their bloodstream,
delivering triglycerides to cells and transferring
cholesterol to other lipoproteins.
Another significant contributor is the high carbohydrate, lowfat diet, which leads to excess glucose in the blood stream, which glycates LDL
particles and renders them ineffective in
delivering cholesterol to the tissues.