Sentences with phrase «cholesterol sulfate»
Cholesterol sulfate is a combination of two natural substances found in our bodies called cholesterol and sulfate. Cholesterol is a type of fat that helps make our cells healthy, and sulfate is a type of molecule that helps with various bodily functions. Putting these two together, cholesterol sulfate is a important chemical that plays a role in maintaining our overall health. Full definition
As a result, you end up with weaken cholesterol formation, which can finally lead to a cholesterol - and cholesterol sulfate deficiency.
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Babies also need cholesterol sulfate in utero, which is significantly reduced when you take a statin.
Muscle cells ordinarily contain significant levels of glutathione, and its depletion leads to mitochondrial damage.23 Patients undergoing surgical trauma have been found to exhibit reduced glutathione levels in their skeletal muscles.21 It is tempting to speculate that cholesterol sulfate provides the sulfur needed for glutathione synthesis, so that the deficiency would be explained by the reduced availability of cholesterol following the immune system's heightened response to surgical trauma.
Furthermore, apparently the body is unable to produce vitamin D3 sulfate directly from unsulfated vitamin D3 19 (which implies that it produces vitamin D3 sulfate directly from cholesterol sulfate).
«That you can use simple metabolites like cholesterol sulfate, which is readily available, to induce differentiation is in my view very powerful if you think about this as a potential drug candidate,» Ulijn adds.
«For example, cholesterol sulfate, which our rigid gel revealed as critical to bone cell differentiation, could be a safer solution (e.g., minimal off - target effects) for treating osteoporosis, spinal fusion, and other bone - related conditions.
One metabolite featured in the study is cholesterol sulfate, which was found to be used up during osteogenesis on a rigid matrix and in turn could be used to convert stem cells into bone - like cells in a dish.
At the end of pregnancy the cholesterol sulfate in the villi rises to levels of about 24 units.
At that point, your body begins to form arterial plaque to compensate for this deficiency, because your platelets can produce the cholesterol sulfate your heart and brain needs within that plaque.
Given that cholesterol sulfate and vitamin D3 sulfate are very similar in molecular structure, I would imagine that both molecules are produced the same way.
However, my extensive literature search has led me to two mysterious molecules found in the blood stream and in many other parts of the body: vitamin D3 sulfate and cholesterol sulfate.35
«Influence of cholesterol sulfate and carbohydrate moieties on rabbit sperm penetration of zonae pellucidae»; The University of Georgia; 1987.