Sentences with phrase «cholesterol transport in»

October 25, 1997 Scientists closing in on how increased Alzheimer's risk is linked to fat and cholesterol transport in the brain Scientists studying the brain are learning how the removal of cholesterol and the proper delivery of fatty compounds are vital for the healthy function of the brain, in an effort to understand how these processes gone awry can lead to Alzheimer's disease.

We plan to apply two recently developed approaches to investigate the distribution and molecular mechanisms of cholesterol transport in C. elegans.

Not exact matches

Interestingly, the soluble fiber in oats attaches to cholesterol molecules and transports them out of the body rather than being absorbed into the bloodstream, which can help lower cholesterol and reduce the risk of heart disease.

Because triglycerides and cholesterol can't dissolve in blood, they circulate throughout your body with the help of proteins that transport the lipids (lipoproteins).

We conclude that apolipoprotein E does not function to remove cholesterol from macrophages but rather to participate in «reverse cholesterol transport.»

The inflammation may block the transport of cholesterol from vessel walls to circulation leading to lower HDL - cholesterol levels in the circulation,» says Dr. Pirkka - Pekka Laurila.

The lipoprotein transport system holds the key to understanding the mechanisms by which genes, diet, and hormones interact to regulate the plasma cholesterol level in man.

In 1993, Poirier and his Montreal - based team co-discovered an important genetic risk factor involved in the most common form of the disease: a defective gene, called Apolipoprotein E type 4 (ApoE4), that prevents the normal transport of cholesterol and phospholipids to the braiIn 1993, Poirier and his Montreal - based team co-discovered an important genetic risk factor involved in the most common form of the disease: a defective gene, called Apolipoprotein E type 4 (ApoE4), that prevents the normal transport of cholesterol and phospholipids to the braiin the most common form of the disease: a defective gene, called Apolipoprotein E type 4 (ApoE4), that prevents the normal transport of cholesterol and phospholipids to the brain.

Enrich points out that «in the cell, cholesterol controls the trafficking of vesicles, which are responsible for transporting integrins to cell surface.

We believe that we can help prevent Aβ deposition in the brain by influencing lipid metabolism and cholesterol transport.

We believe that we can help prevent amyloid - beta deposition in the brain by influencing lipid metabolism and cholesterol transport

These NIH - funded studies investigate the role of Apolipoprotein F (ApoF) in regulating cholesterol transport.

To that end, she genetically engineered mice to lack a protein that transports cholesterol out of cells in order to analyze experimentally what happens when immune cells remain abnormally packed with cholesterol.

We are also studying how apoAI can become dysfunctional so that it can no longer participate in reverse cholesterol transport.

HDL or High - Density Lipoproteins are typically given a halo in the medical world for their role in transporting cholesterol that has been used by the body back to the liver to be excreted as bile.

ApoE stands for Apolipoprotein E, which is a protein that transports fats and cholesterol in the body.

It also transports cholesterol from extra-hepatic sites, including the arterial wall, to the liver for excretion via reverse cholesterol transport.77 Results from IER (60 - 85 % ER / alternate days) trials have thus far been inconsistent, with some reporting decreases 40, and others increases 37, 39, but with the majority showing no effects on HDL cholesterol levels.38, 42, 43, 45, 49, 51, 52Inconsistencies may have arisen due to the biphasic response of HDL documented by studies of ER induced weight - loss, whereby levels typically decrease during active weight - loss then either return to baseline or (less commonly) rise following attainment of weight stability.78 Complementary increases in HDL levels and particle size have been shown when endurance exercise have been combined with IER 42, 46, 47 however further discussion goes beyond the scope of this review.

They are actually lipoproteins, small fat and protein packages that transport cholesterol in the body.

VLDL and LDL transport fats, in the form of triglycerides and cholesterol, from the liver to the body cells.

Cholesterol is found in the blood, attached to lipoproteins for transport, and within the cells.

«Cholesterol, largely transported through the body as LDL - C, has clearly been established as a causal agent in atherosclerosis over many decades of extensive research.

Increased glycated ApoE particles have been detected in the cerebrospinal fluid (CSF) of AD patients.34, 35 The physiological insult of glycated ApoE is that ApoE helps transport LDL particles (and their critical cholesterol and fatty acid passengers) across the blood brain barrier.

The important role of apoproteins in transporting cholesterol in the blood has been documented6 and there has been an immense amount of research tying differences in apoproteins to a possible cause for heart disease.

In addition to fat and cholesterol transport, LDL and HDL both have immune functions.

Inositol metabolizes fats and cholesterol and aids in their transport in blood vessels.

In parallel, it is becoming very clear that cholesterol is pervasive in the brain, and that it plays a critical role both in nerve transport in the synapse and in maintaining the health of the myelin sheath coating nerve fiberIn parallel, it is becoming very clear that cholesterol is pervasive in the brain, and that it plays a critical role both in nerve transport in the synapse and in maintaining the health of the myelin sheath coating nerve fiberin the brain, and that it plays a critical role both in nerve transport in the synapse and in maintaining the health of the myelin sheath coating nerve fiberin nerve transport in the synapse and in maintaining the health of the myelin sheath coating nerve fiberin the synapse and in maintaining the health of the myelin sheath coating nerve fiberin maintaining the health of the myelin sheath coating nerve fibers.

Since apoE plays a critical role in the transport of cholesterol and fats to the brain, it can be hypothesized that insufficient fat and cholesterol in the brain play a critical role in the disease process.

Various nutritional factors found in whole food diets have been found to assist in reverse cholesterol transport (including phospholipids, CLA, and polyphenols).

Cholesterol is most commonly transported in the blood by molecules composed of fat and protein called lipoproteins.

In addition to transporting cholesterolaround the body, HDL collects cholesterol that is not being used by cells and brings them back to the liver to be recycled or destroyed.

One study from UC Davis found walnuts to improve endocrine markers in women with polycystic ovarian syndrome (PCOS), improving cholesterol, insulin response (PCOS is commonly associated with insulin resistance) and sex hormone - binding globulin, which is responsible for the transport of hormones through the body.

Lipoproteins are «transport vehicles» for fat and cholesterol in the body that travel in the blood and vary in size.

Every single cell in our body is surrounded by a lipid membrane made of cholesterol, fatty acids, and protein transport channels.

• Help regulate oxygen uses and energy production • Important in nerve, muscle and cellular functions • Play a vital role in cognitive function, including memory and mood • Involved in regulation of metabolism, body temperature, blood sugar and insulin control, thyroid function, carbohydrate metabolism and control over hormonal processes • Lubricate joints and improve mineralization of bones • Help transport cholesterol • Improve digestion of the gut • Build the immune system and regulate inflammatory response • Can help direct the processes that stimulate fat breakdown and utilization • Helps regulate blood pressure

HDL Cholesterol Also known as «good» cholesterol because of its function in transporting cholesterol away from the tissues (especially arteries) tCholesterol Also known as «good» cholesterol because of its function in transporting cholesterol away from the tissues (especially arteries) tcholesterol because of its function in transporting cholesterol away from the tissues (especially arteries) tcholesterol away from the tissues (especially arteries) to the liver

An effect of walnuts on ex vivo cholesterol efflux was observed with whole serum but not apoB - depleted serum; in addition to HDL, LDL can serve as an acceptor of free cholesterol in the reverse cholesterol transport pathway (39), indicating that walnuts may have a greater effect on global cholesterol efflux than HDL - specific efflux.

Studies suggest that consumption of whole walnuts or their extracted oil can reduce cardiovascular risk, by helping HDL — good cholesterol — perform more effectively in transporting and removing excess cholesterol from the body.