Interactions ANTICHOLINERGIC DRUGS: Theoretically, concomitant use might decrease the effect of drugs with anticholinergic activity, due to the potential
cholinergic activity of DMAE.
The particular ability of Ashwagandha to help assist with mental acuity and reaction time (source), possibly due in part to
cholinergic activity, also makes this herb of particular value to athletes.
However, recent evidence indicates that apoE4 expression compromises the blood - brain barrier (as does apoE deficiency).40 Studies of brain histology, neurodegenerative markers,
cholinergic activity, and neuronal function in knockout mice have been equivocal.39 Failure of detailed neurocognitive and retinal studies to demonstrate defects in our patient suggests either that the functions of apoE in the brain and eye are not critical or that they can be fulfilled by a surrogate protein.
AD, although an irreversible and progressive disorder, is currently treated with palliative, symptomatic therapy: primarily with acetylcholinesterase (AChE) inhibitors to amplify remaining
cholinergic activity.
The in - vivo (animal) study «Enhanced memory in Wistar rats by virgin coconut oil is associated with increased antioxidative,
cholinergic activities and reduced oxidative stress» was published in January of 2017.
Improve
cholinergic activities and the release of acetylcholine in the specific parts of the brain
Not exact matches
Therefore, the effect of J147 on the
cholinergic system was investigated using the muscarinic receptor antagonist, scopolamine, which decreases central
cholinergic neuronal
activity.
Scopolamine is a well known competitive muscarinic receptor antagonist that causes reproducible, transient impairments across multiple cognitive domains in healthy animals and non-diseased humans by decreasing central
cholinergic neuronal
activity [124, 125].
In this study, the effect of lesion of the
cholinergic pedunculo - pontine cell bodies (PPN) by the excitotoxin quisqualic acid was investigated on spontaneous locomotor
activity and learning in rats.
YanGang Sun, Juan Pita - Almenar, Chia - Shan Wu, John J Renger, Victor N. Uebele, Hui - Chen Lu, Michael Beierlein (2013) «Biphasic
cholinergic synaptic transmission controls action potential
activity in thalamic reticular nucleus neurons», Journal of Neuroscience 33: 2048 - 59.
Juan Diego Pita - Almenar, Dinghui Yu, Hui - Chen Lu, Michael Beierlein (2014) «Mechanisms Underlying Desynchronization of
Cholinergic - Evoked Thalamic Network
Activity», Journal of Neuroscience 34 (43): 14463 - 14474.