Sentences with word «choroideremia»

Starting two years ago with Wyatt, they injected a virus carrying a corrective copy of the CHM gene into the retinas of people with choroideremia.

MacLaren is also hopeful of stopping choroideremia before significant loss of vision.

However, MacLaren is hopeful that the therapy could also be used to stop choroideremia before there is any significant loss of vision.

The 65 - year - old is one of six people in the world to receive gene therapy for a rare type of inherited eye disease called choroideremia.

A fault in the CHM gene causes choroideremia, in which cells in the retina stop working and slowly die, leading to blindness.

Robert MacLaren of the University of Oxford and his colleagues decided to see if it could correct choroideremia.

Thus it was fascinating to see positive selection on genes like CHM and CNGB3, in which mutations can cause retinal diseases featuring night blindness (i.e. choroideremia and retinitis pigmentosa) in humans.

Yesterday the BBC News and Guardian Newspaper reported that a team led by surgeon Professor Robert Maclaren at the Oxford Eye Hospital had succeeded in using gene therapy to halt the decline in vision in six patients with the progressive eye disorder choroideremia.

Robert MacLaren of the University of Oxford and his colleagues injected a virus with a corrective copy of the CHM gene into the retinas of people with choroideremia.

Choroideremia is caused by defects in the CHM gene, which produces a protein called REP - 1 and affects one in 50,000 people.

He was one of six people with choroideremia to be treated at least six months ago.

Inherited retinal diseases (IRDs) comprise a heterogeneous group of retinal degenerations, including retinitis pigmentosa, choroideremia, Leber congenital amaurosis, and other dystrophies.

choroideremia, which has caused him to become legally blind.