Sentences with phrase «chromatid chromosome»

According to our current understanding, cohesin is already loaded onto DNA (along the entire length of the decondensed one - chromatid chromosome) in telophase, i.e. only minutes after chromosome segregation, by opening / closing its Smc1 - Smc3 interaction site (or «entry gate»).

Not exact matches

During cell division, chromosomes acquire a characteristic X-shape with the two DNA molecules (sister chromatids) linked at a central «connection region» that contains highly compacted DNA.
Examples of chromosomes with extra links between chromatids, comparing with a normal chromosome (on the left).
In the second stage of meiosis, the single pairs of chromosomes — two sister chromatids joined in the middle — separate and the egg cell divides again in the same way, leaving a single mature egg cell with one copy of each chromosome.
Closer examination of the chromosome - tracking data showed that the dominant type of error was predivision of sister chromatids, and not movement of intact chromosome pairs to only one of the new cells.
From S - phase onward, the two copies of each chromosome (referred to as sister chromatids) are connected by molecular rings and each copy attempts to establish attachments to spindle microtubules that emanate from two spindle poles.
This not only ensures that sister chromatids remain cohesed until the metaphase - to - anaphase transition, but also provides us with the stereotypical image of an X-shaped chromosome.
It is important to mention that cohesin also has a very unique role in meiosis where it not only coheses sister chromatids but also chromosomal homologs (the two maternal / paternal versions of a chromosome, each consisting of two sisters, which themselves are cohesed).
Meiotic cohesin STAG3 is required for chromosome axis formation and sister chromatid cohesion.
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