Sentences with phrase «chromosome abnormalities in»

The high incidence of chromosome abnormalities in clinically recognised pregnancies is well documented, but experience of these problems at the time of conception is extremely limited.

Worse still, the genetic errors in those eggs led to chromosome abnormalities in 40 percent of the next generation's eggs.

About 4 percent of couples with recurrent miscarriages have chromosome abnormalities in one or both parents that can recur in future pregnancies, so some physicians suggest parental karyotype tests as a part of investigating the cause.

Not exact matches

Screening tests tell your doctor the risk that your baby might have an abnormality in his or her genes or chromosomes.

The most common cause of first - trimester miscarriages is chromosomal abnormalities in the baby, especially trisomy (three copies of one or more of the 23 chromosome pairs).

They found that an enzyme in yeast cells degrades the ends of certain chromosomes, leaving them prone to further abnormalities.

Another staining technique called comparative genome hybridisation (CGH), which labels all chromosomes, has previously been used to analyse abnormalities in the polar body — a chromosome - containing sac expelled from the egg shortly after fertilisation.

«What drives the decline in oocyte quality in human females is chromosome abnormalities,» Hassold says.

As with humans, he says, the oocytes of C. elegans also show an increase in chromosome abnormalities with aging.

Down syndrome is the most common chromosomal abnormality in humans, involving a third copy of all or part of chromosome 21.

27 percent reduction in conotruncal defects, or severe heart outflow tract abnormalities; 23 percent reduction in coarctation of the aorta — a narrowing of the major artery (the aorta) that carries blood to the body; 15 percent reduction in atrial and ventricular septal defects — holes in the wall separating heart chambers; however, no changes were seen with regard to chromosomally associated defects — abnormality in the number of an infant's chromosomes.

Recombination ensures that each gamete ends up with a unique copy of every chromosome, but when the process goes awry, it can result in chromosomal abnormalities.

Current prenatal screening protocols for common structural abnormalities in the chromosomes vary among countries and medical practices.

Scientists worry that although there hasn't been an obvious increase in birth defects so far, sex chromosome abnormalities may show up when the children reach puberty.

Bearden's earlier research had focused on children with abnormalities caused by missing sections of genetic material on chromosome 22, in a location known as 22q11.2.

It's not clear how that may have happened, because large deviations in the amount of DNA usually kills fetuses or renders them infertile because of abnormalities in the amounts of various proteins produced or because organisms can not tolerate having extra copies of sex chromosomes.

For the first time, scientists have directly observed events that lead to the formation of a chromosome abnormality that is often found in cancer cells.

Perera's paper in Cancer Epidemiology Biomarkers and Prevention linked the chromosomal aberrations, which were somewhat higher than normal, to air pollution: On average, the higher the hydrocarbons in the mothers» air, the more frequent the abnormalities seen in the infants» chromosomes.

The other marker is an aberrant pattern in the chromosomes; the DNA shows a greater number of abnormalities than normal, including DNA that is missing or moved.

For some inexplicable reason, the chromosomes in 40 % of the eggs looked abnormal — a wild jump from the 1 % to 2 % abnormality her lab typically observes.

Her finding provided one of the first indications that chromosome abnormalities could play a role in cancer.

«Ninety percent of human tumors have chromosome abnormalities, and we know that many of these are made possible by mutations in p53,» says Holland.

The Philadelphia chromosome or Philadelphia translocation (Ph) is a specific genetic abnormality in chromosome 22 of leukemia cancer cells (particularly chronic myeloid leukemia (CML) cells).

«In fact, abnormal cells with numerical and / or structural anomalies of chromosomes have been observed in as many as 80 - 90 % of human early stage embryos following in vitro fertilization,» says Professor Thierry Voet from the Wellcome Trust Sanger Institute, UK, and the University of Leuven, Belgium, another senior author of this paper, «and CSV tests may expose some degree of these abnormalities.&raquIn fact, abnormal cells with numerical and / or structural anomalies of chromosomes have been observed in as many as 80 - 90 % of human early stage embryos following in vitro fertilization,» says Professor Thierry Voet from the Wellcome Trust Sanger Institute, UK, and the University of Leuven, Belgium, another senior author of this paper, «and CSV tests may expose some degree of these abnormalities.&raquin as many as 80 - 90 % of human early stage embryos following in vitro fertilization,» says Professor Thierry Voet from the Wellcome Trust Sanger Institute, UK, and the University of Leuven, Belgium, another senior author of this paper, «and CSV tests may expose some degree of these abnormalities.&raquin vitro fertilization,» says Professor Thierry Voet from the Wellcome Trust Sanger Institute, UK, and the University of Leuven, Belgium, another senior author of this paper, «and CSV tests may expose some degree of these abnormalities.»

Previous reports have shown that in a genetic abnormality called Philadelphia chromosome, fusion of ABL and BCR genes cause leukemia.

A genetic disorder is caused by abnormalities in genes or chromosomes.

This response led to a discussion about abnormalities in chromosome formation and how this leads to specific genetic diseases.

It derives from pericytes associated with blood vessels and, at least in some cases, involves a chromosome abnormality (usually an extra or an absent chromosome).

Scientists working to sort out hundreds of thousands of genes found that some sequences on canine chromosomes are similar to some sequences on human chromosomes and can therefore lead to the discovery of markers for some diseases or abnormalities in both species.