Sentences with phrase «chromosome segregation protein»

We further aim to understand origins and causes for evolutionary diversity in chromosome segregation protein networks, using various model organisms including Tetrahymena thermophila and Toxoplasma gondii.

Not exact matches

From graduate school and two postdocs to my first nontenure - track faculty position, I haven't lost my desire to push forward, bit by bit, the frontiers of my field — to watch with increasing precision the dance of proteins, DNA replication and repair, and chromosome segregation.

Members of the kinesin superfamily of motor proteins are essential for mitotic and meiotic spindle organization, chromosome segregation, organelle and vesicle transport, and many other processes that require microtubule - based transport.

In this study, the last three amino acids of the Pten protein, which are often missing in human cancers, were found to be critical for forming an intact mitotic spindle, a structure required for accurate chromosome segregation.

Kinetochore targeting of fission yeast Mad and Bub proteins is essential for spindle checkpoint function but not for all chromosome segregation roles of Bub1p.

mSin3 - associated protein, mSds3, is essential for pericentric heterochromatin formation and chromosome segregation in mammalian cells.

To address key questions of meiotic ploidy reduction, we screen for and characterise novel meiotic proteins, focusing on proteins that are specifically involved in meiotic chromosome segregation and chromosome dynamics in mice.

Cheeseman and his laboratory have focused on three key groups or complexes of proteins that play essential roles in chromosome segregation in human cells.

Perhaps the best known example of intracellular protein patterning is the molecular machinery that orchestrates the regular segregation of complete chromosome sets to the two daughter cells during cell division.

Architecture of protein complex hints at its foundational function in chromosome segregation