Discovered two proteins crucial for proper partitioning of
chromosomes during meiosis (improper partitioning is a major cause of human birth defects)
Two proteins she discovered help ensure proper partitioning of
chromosomes during meiosis (improper partitioning is a major cause of human birth defects).
Appropriate dynamics and behavior of
chromosomes during meiosis are essential to genetic integrity and reproductive success.
Not exact matches
Thawing caused ice crystals to form and prevented
meiosis, the cellular process
during which an egg's
chromosomes split up from 46 to 23, to be united later with 23
chromosomes from a sperm cell.
To understand his hypothesis, consider that
during the formation of a woman's eggs, paternal and maternal X
chromosomes recombine
during meiosis.
Like others before him, Schrödinger was struck by the fact that
chromosomes are accurately duplicated
during ordinary cell division (mitosis, the way in which an organism grows) and
during the creation of the sex cells (
meiosis).
Meiosis uses many of the same biochemical mechanisms employed
during mitosis to accomplish the redistribution of
chromosomes.
During meiosis, the cell copies all its
chromosomes, pairs them up, and shuffles sections of genetic material between the arms of the paired or homologous
chromosomes.
Because the
chromosomes of each parent undergo genetic recombination
during meiosis, each gamete, and thus each zygote, will have a unique genetic blueprint encoded in its DNA.
During meiosis, the genome of a diploid germ cell, which is composed of long segments of DNA packaged into
chromosomes, undergoes DNA replication followed by two rounds of division, resulting in haploid cells called gametes.
The researchers genetically engineered the worm so that PP4 was functionally disabled, and then observed the consequences of its absence on
chromosome regulation
during meiosis.
Failure has often struck at the stage of
meiosis, a type of cell division
during which paired
chromosomes swap DNA and the number of
chromosomes per cell is halved.
Recombination refers to the formation of new combinations of genes naturally
during meiosis, which is a stage of the cell cycle where
chromosomes pair up and undergo exchange.
Something seemed to have gone terribly wrong
during meiosis, the process that separates
chromosomes so that when egg and sperm come together they each contribute half the genetic material to an embryo.
During meiosis, telomeres allow
chromosomes to attach to the nuclear membrane, thus allowing them to exchange DNA fragments.
Heritable genetic variation is the result of genome instability
during germ cell development, instability that arises through mutation,
chromosome rearrangement or
chromosome mis - segregation
during mitosis or
meiosis.
During meiosis, homologous
chromosomes, one from the mother and the other one from the father, pair with each other and exchange parts (recombine).
To understand this lesser known phenomenon, the Cole lab (Zelazowski M et al, Cell, 2017) has directly studied
chromosome recombination
during male
meiosis in juvenile and adult mice.
Finsterbusch F, Ravindranathan R, Dereli I, Stanzione M, Tränkner D, Tóth A Alignment of homologous
chromosomes and effective repair of programmed DNA double - strand breaks
during mouse
meiosis require the minichromosome maintenance domain containing 2 (MCMDC2) protein.
Activity includes: • original cells in Prometaphase I showing bivalents and chiasma • cells in Prophase I showing
chromosome line up
during independent assortment • resulting gametes • (includes also - for an easier activity - cells in Interphase II showing cells after first round of division) Students to find matching cards (Prometaphase I, Prophase I and 4 resulting gametes) Aim: to get a greater appreciation of the variety in gametes created through crossing over and independent assortment
during meiosis Print, laminate, chop up all cards, mix them up, go!