Read the full paper titled Intranasal administration of mesenchymoangioblast - derived mesenchymal stem cells abrogates airway fibrosis and airway hyperresponsiveness associated with
chronic allergic airways disease published in the FASEB Journal.
Lead researchers Associate Professor Chrishan Samuel and Dr Simon Royce tested the efficacy of the MSCs on three key components of asthma in a preclinical model of
chronic allergic airways disease: inflammation; airway remodeling (structural changes that occur in lungs as a result of prolonged inflammation); and airway hyperresponsiveness (the clinical symptom of asthma).
Not exact matches
«Asthma and
airway allergic responses are among the most common
chronic diseases in childhood affecting more than 6 million children in the US,» said John Wherry, Ph.D., Deputy Editor of the Journal of Leukocyte Biology.
Career Goals: Developing of novel immunotherapeutic strategies for the treatment of
chronic allergic inflammation and
airway remodeling.
Objectives: This study investigated comorbidity in chemical intolerance (CI) and building - related intolerance (BRI) with (i)
chronic sinusitis,
chronic obstructive pulmonary disease,
allergic and nonallergic asthma and
allergic rhinitis, and (ii)
airway inflammatory symptoms.
The combination of vitamins E and C to enhance
airway antioxidant levels in people with
allergic asthma and reduce the incidence of preeclampsia among pregnant women with
chronic hypertension or a history of preeclampsia / eclampsia
Coughing can be a symptom of several maladies, including heartworm disease,
chronic obstructive pulmonary disease,
allergic bronchitis, cardiomyopathy, congestive heart disease, lung cancer, and several other pathologies that can affect the upper and lower
airways.
Asthma in cats is best defined as
chronic allergic bronchial
airway disease.
Criteria Description PRIORITY Carcinogenicity Potential to cause cancer Endocrine Disruption Potential to negatively effect hormone function and impact development Mutagenicity Potential to damage DNA Teratogenicity Potential to harm fetus Reproductive Toxicity Potential to negatively impact reproductive system ADDITIONAL Acute Toxicity Potential to cause harm upon initial, short term exposure
Chronic Toxicity Potential to cause harm upon repeated, long - term exposures Irritation of Skin and Mucous Membranes Potential to irritate eyes, skin, and respiratory system Sensitization Potential to cause
allergic reaction upon exposure to skin or
airways Other Any additional characteristic (e.g., flammability, skin penetration potential, etc.) relevant to the overall evaluation but not included in the previous criteria