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Chronic exposure to drugs of abuse causes changes in the brain that could underlie the transition from casual drug use to addiction.
Dr. Chartoff is interested in how
chronic exposure to drugs of abuse changes the brain at molecular and cellular levels such that drug withdrawal elicits a protracted constellation of negative affective signs.
Not exact matches
To help prevent your child from joining the growing statistics of chronic health problems, early gut healing and continued gut health efforts are worthwhile, especially if your child expresses any of the symptoms of concern discussed in this book, has been exposed early to antibiotic drugs, has had early exposure to formula feeding, or has experienced multiple GI infection
To help prevent your child from joining the growing statistics of
chronic health problems, early gut healing and continued gut health efforts are worthwhile, especially if your child expresses any of the symptoms of concern discussed in this book, has been exposed early
to antibiotic drugs, has had early exposure to formula feeding, or has experienced multiple GI infection
to antibiotic
drugs, has had early
exposure to formula feeding, or has experienced multiple GI infection
to formula feeding, or has experienced multiple GI infections.
Ok, so we have billions of pounds of synthetic chemicals consumed every year as patented
drugs, with an army of degreed, licensed and doctored foot soldiers prescribing them recklessly under the once great banner of «medicine,» in an ongoing war against the body's virtually infinite potential
to generate symptoms, most of which are — ironically — a means
to heal from acute or
chronic exposure to synthetic chemicals.
Cellular - level changes
to a part of the brain's reward system induced by
chronic exposure to the psychoactive component of marijuana may contribute
to the
drug's pleasurable and potentially addictive qualities, suggests a study in young mice published in JNeurosci.
Due
to effects of multigenerational poverty, limited educational and economic opportunities, high levels of
drug use and trade, and pervasive community violence, urban youth in Baltimore and many US cities are at increased risk for
exposure to a variety of stresses, including early life stress, recurrent and
chronic stress, and
exposure to significant and / or recurrent traumas.
Felitti and colleagues1 first described ACEs and defined it as
exposure to psychological, physical or sexual abuse, and household dysfunction including substance abuse (problem drinking / alcoholic and / or street
drugs), mental illness, a mother treated violently and criminal behaviour in the household.1 Along with the initial ACE study, other studies have characterised ACEs as neglect, parental separation, loss of family members or friends, long - term financial adversity and witness
to violence.2 3 From the original cohort of 9508 American adults, more than half of respondents (52 %) experienced at least one adverse childhood event.1 Since the original cohort, ACE
exposures have been investigated globally revealing comparable prevalence
to the original cohort.4 5 More recently in 2014, a survey of 4000 American children found that 60.8 % of children had at least one form of direct experience of violence, crime or abuse.6 The ACE study precipitated interest in the health conditions of adults maltreated as children as it revealed links
to chronic diseases such as obesity, autoimmune diseases, heart, lung and liver diseases, and cancer in adulthood.1 Since then, further evidence has revealed relationships between ACEs and physical and mental health outcomes, such as increased risk of substance abuse, suicide and premature mortality.4 7