"Chronic hyperglycemia" refers to a long-term condition where the level of sugar (glucose) in the blood is consistently high.
Full definition
Thus, increased MYCL does not appear to be an early marker in the pathogenesis of diabetes but a consequence
of chronic hyperglycemia (228).
Because chronic hyperglycemia... potentially predicts a poor therapeutic effect of aerobic exercise on glycemic control and fitness, using exercise to treat patients with poorly controlled T2DM may have limited chances of a successful outcome,» the study concludes.
Other research published in Frontiers in Pharmacology suggests moringa may be useful in
treating chronic hyperglycemia and hyperlipidemia, two risk factors for diabetes.
I've always been overly stressed and have had sleep problems since I was a kid, so my guess is that
the chronic hyperglycemia has disrupted my parasympathetic nervous system, causing an decrease in the cholinergic anti-inflammatory pathway (joint problems) and also the nervousness / sleeplessness / anxiety problems.
Specifically,
chronic hyperglycemia and hyperinsulinemia induced by high glycemic load carbohydrates may elicit a number of hormonal and physiologic changes that promote insulin resistance (71,77,78).
But
chronic hyperglycemia has caused Grayson to develop proliferative retinopathy, a severe form of eye disease.