Sentences with phrase «chronic hyperinsulinaemia»
However, chronic hyperinsulinaemia, which is present in insulin - resistant mothers and corresponds to high insulin levels in the fetus, might induce insulin resistance in the fetal brain.»
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According to the «Twin Cycle Hypothesis», chronic energy excess (in the presence of skeletal muscle IR) results in a compensatory hyperinsulinaemia in an attempt to maintain normoglycemia, however will also promote the accumulation of intrahepatic lipid (IHCL) via the stimulation ofde novo lipogenesis.
There is evidence that hyperinsulinaemia, hyperglycaemia and chronic inflammation may affect the neoplastic process through various pathways, including the insulin / IGF -1 pathway, and most cancer cells express insulin and IGF - 1 receptors.