In addition, the body's attempt to rid itself of the worms results in
chronic immune stimulation, which further complicates the disease.
Not exact matches
Senior author Madhav Dhodapkar, M.D., the Arthur H. and Isabel Bunker Professor of Medicine and Immunobiology, and chief of Hematology, said the study, using tissue and blood samples from humans and mice, shows that
chronic stimulation of the
immune system by lipids made in the context of inflammation underlies the origins of at least a third of all myeloma cases.
«[It] supports this idea that
chronic inflammation in children, perhaps through exposure to bacterial endotoxin in the gut, is causing these different
immune cell populations to be non-responsive to cytokine
stimulation,» Petri said.