Sentences with phrase «chronic phase»

A pet may have the disease for several years before reaching an often fatal chronic phase.

Researchers at the Center for BrainHealth at The University of Texas at Dallas have identified complex brain connectivity patterns in individuals with chronic phases of traumatic brain injury which may explain long term higher order cognitive function deficits.

«Although TKIs such as the first - generation TKI imatinib mesylate (IM) and the second - generation TKIs dasatinib and nilotinib have markedly improved the prognosis of patients with chronic phase CML, a cure remains elusive.

«To our knowledge, this is the first randomized trial regarding the discontinuation of imatinib in first chronic phase CML patients who have achieved a durable and stable molecular response,» the authors wrote.

Low - dose donor CD8 + cells in the CD4 - depleted graft prevent allogeneic marrow graft rejection and severe graft - versus - host disease for chronic myeloid leukemia patients in first chronic phase.

The relatively mild acute phase of Chagas disease is followed by the more dangerous chronic phase, during which parasites take up residence in the host, mostly in the heart and stomach muscles.

It is used to treat chronic phase and accelerated phase Philadelphia chromosome positive chronic myelogenous leukemia (Ph + CML).

During the execution and chronic phases of disease, the researchers identified a number of genes involved in programmed cell death, or apoptosis, that had noticeably different patterns of expression between the diseased and normal dogs.

An ideal Chagas vaccine would prevent infection altogether, but one that prevents the complications during the chronic phase by keeping parasite numbers low would eliminate most of the disease burden.

The mice were fed either a control diet or one containing resveratrol from days 35 to 48 (the chronic phase).

They assessed gene activity at time points known to correspond with key phases of disease: the «induction phase,» the time before the peak level of photoreceptor cell death; the «execution phase,» when the highest rates of photoreceptor cell death occur; and the «chronic phase,» during which photoreceptor cell death continues at somewhat reduced levels.

As anticipated, mice infected with Type II parasites succumbed to infection during both the acute and chronic phase.

[2] An animal study showed that 4 mg / kg / d curcuminoid reduced joint swelling by 75 % during the acute phase and 68 % during the chronic phase.

Curcumin appears to be effective in treating RA throughout the course of the disease including both acute and chronic phases of disease.

Many dogs can overcome the infection on their own, but others may enter a subclinical or chronic phase of infection, which can be much more difficult to clear and / or treat.

Some dogs eventually progress to the chronic phase, where very severe illness can develop.

In practice, it is difficult to differentiate the acute and chronic phases.

Finally, some dogs enter the chronic phase where very serious illnesses may result from the infection.

Untreated dogs and some treated dogs may progress to the subacute and chronic phases.2 Subacute phase ehrlichiosis:

Dogs that are infected may continue to shed the organism, they may totally eliminate the organism during this stage or they may progress to the chronic phase of the disease.

Dogs that are in the chronic phase with a weakened immune system have a poor prognosis and a lower rate of survival.