Sentences with phrase «chronic phases of»

Curcumin appears to be effective in treating RA throughout the course of the disease including both acute and chronic phases of disease.

Many dogs can overcome the infection on their own, but others may enter a subclinical or chronic phase of infection, which can be much more difficult to clear and / or treat.

Not exact matches

Reldesemtiv is the subject of three ongoing Phase 2 clinical trials enrolling patients with spinal muscular atrophy, chronic obstructive pulmonary disease and amyotrophic lateral sclerosis.

When a child or adolescent has chronic agonies of shyness, these feelings should not be taken as «just a phase.»

Urging clergy and men of religion to renew or revive the practice of prayer, particularly meditation; (2) Distinguishing between the use of alcohol which does not produce a chronic alcoholic and that in which there is «the allergic nature of true alcoholism»; (3) Stressing that «elimination of the phenomenon of craving that follows the treatment does not constitute a cure [but that] the final cure rests with themselves [alcoholics in the second phase of alcoholism]»; (4) Advocating «moral psychology» in achieving entire recovery from alcoholism; (5) Describing the success of the AA.

I agree with Dr. Wiessbluth when he says that children who are out of phase behave as if they have chronic jet lag syndrome.

Narratives range from humorous to heart - wrenching: a teen is smitten by an older boy, a son battles drug addiction, a parent steals the unthinkable, a daughter and her family navigate thunderstorms, a mother redefines «home» for her autistic son — plus compelling essays on parenting teens with chronic illness or anxiety disorders or that inevitable phase of parenting which requires letting go of your teenager.

«Although TKIs such as the first - generation TKI imatinib mesylate (IM) and the second - generation TKIs dasatinib and nilotinib have markedly improved the prognosis of patients with chronic phase CML, a cure remains elusive.

Results from three Phase III clinical trials (ION - 1, ION - 2 and ION - 3) evaluating the investigational once - daily fixed - dose combination of the nucleotide analogue polymerase inhibitor sofosbuvir (SOF) 400 mg and the NS5A inhibitor ledipasvir (LDV) 90 mg, with and without ribavirin (RBV), for the treatment of genotype 1 chronic hepatitis C virus (HCV) infection have been presented at the International Liver CongressTM 2014.

«Although safety and effectiveness in treating episodic and chronic migraine still have to be confirmed in phase three studies, I am confident that we will have access to new medicines that have been specifically developed for this indication to help us tackle the problem of primary headache,» Prof Sprenger added.

It is believed that chronic wounds get stuck in an inflammatory phase, with a low - oxygen microenvironment and the persistent presence of enzymes that break down tissue proteins.

Results of a phase 2 study published in The Lancet suggest that simvastatin, a cheap cholesterol lowering drug, might be a potential treatment option for the secondary progressive, or chronic, stage of multiple sclerosis (MS), which is currently untreatable.

With approximately two - thirds of responders to AF - 219 treatment showing more than a 50 % reduction in cough frequency, we plan to advance the development of AF - 219 by initiating a Phase 2b study in patients with chronic cough early next year and to initiate other studies in preparation for registration studies.»

Afferent Pharmaceuticals today announced publication of results from a Phase 2 clinical trial demonstrating that the company's novel drug candidate, AF - 219, reduced daytime cough frequency by 75 % compared to placebo in patients with treatment - refractory chronic cough.

In collaboration with various rehabilitation clinics, the RUB researchers have tested the feasibility of passive stimulation as a therapeutic option: about 50 patients were treated after a stroke (sub-acute phase) and several chronic patients were treated long - term over many months.

This Phase 3 randomized, double - blind study included 763 adults with chronic HCV genotype 1 infection, a form of the virus found in up to 75 percent of infections, and compensated liver diseases, who had previously not responded or only partially responded to at least one course of peginterferon and ribavirin.

The results of two phase 3 clinical trials that led to FDA approval of adalimumab for treatment of the chronic inflammatory skin disease hidradenitis suppurtiva (HS) are being published in the August 4 New England Journal of Medicine.

They assessed gene activity at time points known to correspond with key phases of disease: the «induction phase,» the time before the peak level of photoreceptor cell death; the «execution phase,» when the highest rates of photoreceptor cell death occur; and the «chronic phase,» during which photoreceptor cell death continues at somewhat reduced levels.

If their phase I clinical trial to test the safety and preliminary efficacy of this therapy gains approval, University of Pittsburgh researchers will test the therapy on 10 patients who suffer from chronic ischemic stroke — the most common form, in which clots block blood flow.

A Phase III Randomized Open - Label Multi-Center Study of Ruxolitinib vs. Best Available Therapy in Patients with Corticosteroid - Refractory Chronic Graft vs Host Disease after Allogenic Stem Cell Transplantation (REACH 3)

Allogeneic Sibling Donor Peripheral Blood Stem Cells Transplantation With Myeloablative Conditioning for Chronic Myeloid Leukemia in Blast Crisis - Successful Treatment Despite Severe Phase of the Disease

She served on the End Point Response Committee for the Blood and Marrow Transplant Clinical Trials Network national randomized phase III clinical trial for treatment of chronic GVHD.

An antibody therapy against a key inflammatory molecule involved in migraines reduces the number of headaches that chronic migraine patients experience per month in a phase III trial A new s...

Ponatinib Extends Survival Over Transplant in Chronic Phase CML: The results of a new study that included patients from the PACE trial and the European Bone Marrow Transplant registry revealed that treatment with ponatinib yielded better overall survival (OS) compared with allogeneic stem cell transplantation (allo - SCT) in patients with chronic phase chronic myeloid leukemia (CP - CML) with a T315I muChronic Phase CML: The results of a new study that included patients from the PACE trial and the European Bone Marrow Transplant registry revealed that treatment with ponatinib yielded better overall survival (OS) compared with allogeneic stem cell transplantation (allo - SCT) in patients with chronic phase chronic myeloid leukemia (CP - CML) with a T315I mutaPhase CML: The results of a new study that included patients from the PACE trial and the European Bone Marrow Transplant registry revealed that treatment with ponatinib yielded better overall survival (OS) compared with allogeneic stem cell transplantation (allo - SCT) in patients with chronic phase chronic myeloid leukemia (CP - CML) with a T315I muchronic phase chronic myeloid leukemia (CP - CML) with a T315I mutaphase chronic myeloid leukemia (CP - CML) with a T315I muchronic myeloid leukemia (CP - CML) with a T315I mutation.

A phase I study of dasatinib in children and adolescents with chronic myeloid leukemia (CML) and other malignancies determined dosing for further studies and suggested the drug is well tolerated and effective in these patients.

In the early phase of CML — known as the chronic stage — the body accumulates too many white blood cells, but these cells mature and function properly, and symptoms are not serious.

Currently, the CDK9 inhibitor flavopiridol is being evaluated in several phase I and II clinical trials for its anti-cancer effects either as a single agent or in combination with other drugs in treatment of esophageal cancer, B - cell chronic lymphocytic leukemia, endometrial carcinoma, recurrent / metastatic squamous cell carcinoma and most relevantly, previously treated locally advanced or metastatic breast cancer (http://www.cancernetwork.com/review-article/current-clinical-trials-flavopiridol/page/0/2).

The moment you are diagnosed with a chronic illness, you go through the phases of grief.

We have to thank our physical and mental response to danger, commonly known as stress, for keeping us safe and sound through all phases of evolution, including the present one, but chronic stress is more like a nasty side - effect to the unbalanced relation between the hectic progress of the modern lifestyle and our relatively slower adaptation to it as organisms.

Thanks to virus - fighting drugs (antiretrovirals), this asymptomatic period, known as the «chronic» or «latency» phase of the disease, can essentially be extended indefinitely.

Metagenics UltraClear Plus supports the management of chronic fatigue syndrome or fibromyalgia and is a medical food that is designed for patients who may benefit from additional support for Phase I and Phase II hepatic detoxification function.

When it comes to fighting cancer and chronic disease, supporting phase II detoxification seems to take the lion's share of responsibility.

Deficiency of «phase II» nutrients is a common finding with most chronic conditions.

A few Refs: http://labtestsonline.org/understanding/analytes/ferritin/tab/test «Ferritin is an acute phase reactant and thus may be increased in people with inflammation, liver disease, chronic infection, autoimmune disorders, and some types of cancer»

He found that they go through different phases of in their response when exposed to chronic stress, and then ultimately sort of shut down and are unable to maintain normal health — i.e. symptoms emerge.

Once the underlying causes of chronic absenteeism have been determined in Phase 1 sessions, it is time to ensure that eective, ecient and consistent systems are in place to improve attendance.

Dr. Monavvari is seeking funding for the third phase of the study, a populationbased study focusing on overall well - being and health measured through quality of life scores and chronic disease management.

Acute conditions usually subside quickly, typically within one phase of treatments, while chronic conditions can be controlled with regular treatments.

Dogs that are in the chronic phase with a weakened immune system have a poor prognosis and a lower rate of survival.

The last stage is the chronic or terminal phase of the infection.

In Ontario for example, K. Wing, a chronic care facility operated by the Sunnybrook Medical Centre under terms of an agreement with the Department of Veterans Affairs («DVA»), was phasing out male orderlies and replacing them with nursing assistants, the vast majority of whom were female.

I also treat various depressive and mood disorders, bereavement, relationship problems, adjustment and phase of life concerns, anger management, and chronic pain.»

I have worked with a wide variety of clientele including school - aged children, adults with serious mental illness (Bipolar Disorder, Psychosis), substance abusers, military personnel (both active duty and retired), and other adults who are struggling with depression, anxiety, chronic pain, trauma, marital distress, and phase of life / adjustment problems.

Phase 1 therapeutic alliance and negative mood regulation skills predicted Phase 2 exposure success in reducing PTSD, suggesting the value of establishing a strong therapeutic relationship and emotion regulation skills before exposure work among chronic PTSD populations.

STAIR / MPE is a sequential, two - phase treatment based in a developmental model which is designed to be sensitive to the disturbances in attachment, emotion regulation, and interpersonal functioning that survivors of childhood or chronic interpersonal violence often bring to treatment.