Sentences with phrase «chronic social defeat»

The current series of studies present findings from two animal models of PTSD, namely the mouse chronic social defeat (CSDS) model (Berton et al., 2006; Golden et al., 2011) recently developed in collaboration with Dr. Eric Nestler and also the fear - conditioned, Wistar - Kyoto (WKY) rat model (DaSilva et al., 2011; 2013).

The Chronic Social Defeat Stress (CSDS) mouse model has received much interest recently as it closely mimics the dynamic range of individual responses to stressors such as the development of a major depressive disorder, anxiety, post-traumatic stress disorder or resil ¬ iency to these disease states.

Then they recorded brain activity as these mice were subjected to a stressful situation called chronic social defeat.

To demonstrate the effects of bullying, the researchers used an animal model simulating the physical and emotional stressors involved in human bullying — chronic social defeat stress.

Looking inside the brains of animals exposed to chronic social defeat stress, the scientists observed hyperactive firing of neurons in the ventral tegmental area (VTA), a critical part of a reward circuit.