The cilia beating frequency varied across samples but the difference was typically within a few hertz.
Further increasing the formaldehyde concentration to 1 milligram per cubic meter led to a dramatic increase — up to 136.4 per cent — in
cilia beating frequency relative to the baseline value.
By enabling the observation of
cilia beating frequency, the experimental model described in this work provides more realism for clinical applications.
In contrast, when air mixed with 0.5 milligrams per cubic meter of formaldehyde was passed through the chamber, they observed a 7.4 per cent increase in
cilia beating frequency relative to the baseline value.
At even higher formaldehyde concentrations of 3.0 milligrams per cubic meter, however, the researchers observed an unexpected decrease in
cilia beating frequency, possibly due to irreversible cell damage caused by the formaldehyde.
When fresh air was passed into the chamber, the researchers observed a 3 per cent drop in
cilia beating frequency relative to the baseline value.
Not exact matches
Wei Wang and Zhi Ping Wang at the A * STAR Singapore Institute of Manufacturing Technology, De Yun Wang at the National University of Singapore and co-workers have now developed the first microfluidic device that enables the direct observation of
cilia and their
beating frequency on a polyester membrane [1].
A paramecium moves by the
beating of its
cilia; an amoeba, by the streaming of its cytoplasm; a muscle, by its over-all contraction.
The
beating rate of
cilia could provide an additional tool to help decide time of death, especially if it was within the previous 24 hours.
They hope to use the
cilia to judge time of death since not only does the
beating slow gradually but it also seems relatively immune to environmental factors.
Since the
beating of these
cilia slows at a predictable rate, forensic teams should be able to estimate time of death more accurately.
RFX3 governs growth and
beating efficiency of motile
cilia in mouse and controls genes involved in human ciliopathies.
The respiratory system has defense mechanisms which protect the epithelium against bacterial infection and foreign particles / molecules from being deposited.29 These mechanisms can be summarized to the following: a)
beating cilia, b) mucus, c) macrophages, d) transporters and e) enzymes.
An underlying respiratory disease such as; asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis modifies these mechanisms by reducing the function of
beating cilia and increasing the production of mucus.