Sentences with phrase «cilia function»

On the other hand, if a dog were to inherit only one PCD gene and a normal one from the other parent, then it is possible that half of the cilia function normally and the other half doesnʼt.

In a report published on September 30 in Nature Genetics, Katsanis and his team used a small transparent fish, zebrafish, to literally watch what happened if they chemically blocked the production of three proteins that are required for primary cilia function during the period when a fish egg develops into a grown up, fully - finned fish.

Not exact matches

The scientists now believe that the loss of normal function in the primary cilium leads to the uncontrollable division of renal epithelial cells, which contributes to the formation of ccRCC.

We then focused in on some of the biochemical processes that are required for a functioning cilium.

We also aim at understanding how different cilia are built and we use drosophila as a model system to understand the specialized function of ciliary genes in different ciliated cells and ciliary sub-compartments.

In humans, defects in cilia assembly or function are responsible for a wide range of diseases called ciliopathies.

An underlying respiratory disease such as; asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis modifies these mechanisms by reducing the function of beating cilia and increasing the production of mucus.

In human cells, mebendazole suppressed the formation of the primary cilium, a microtubule - based organelle that functions as a signaling hub for Hh pathway activation.

It is still unclear if the cilia are directly involved in the cause of the epilepsy and other diseases, or if the relevant proteins function in other, non-ciliary ways to cause disease.

«One of the main causes of male infertility is the cilia won't function properly.»

Cilia are highly conserved organelles that play various motile and sensory functions in many eukaryotes.

In addition, the older of the two centrioles can also function as a basal body seeding the growth of cilia or flagella.

In addition, Tetrahymena possess hundreds of cilia and has complicated microtubule structures, making it an optimal model to illustrate the diversity and functions of microtubule arrays.

Cilia play an important role in many biological functions throughout the body.

Improperly functioning cilia There are people who suffer from a medical condition that affects the cilia's ability to move mucus out of the sinus cavities.

The gene product's precise role is not currently understood but it is thought to anchor regulatory complexes at the photoreceptor connecting cilium, which acts as a bridge between the inner and outer segments of photoreceptor cells [43] as well as having functions in disk morphogenesis [42] and in the structure of the ciliary axoneme [44].