Sentences with phrase «cilia in»

Another main trigger is the involuntary movement of the hairlike cilia in the respiratory tract which remove foreign matter from the air before it gets into the lungs, but other underlying causes can include mucous irritation, obstruction of the nasal passage, inflammation, excess nasal discharge or secretion, pneumonia, chronic vomiting, GI disease, and nasal tumors and dental diseases in older dogs.
Distichiasis is similar to, but not the same as, ectopic cilia, a condition that also occurs in dogs (for more details on this condition, please see the handout «Ectopic Cilia in Dogs»).
Even though aberrant cilia in contact with the corneal surface are assumed to cause corneal irritation, distichiasis in the dog may be clinically insignificant in some individuals [8, 19].
Because knockdown of Tuba in zebrafish affects cilia in a number of organs, including the brain, a variety of aberrant phenotypes were seen in the Tuba knockdown zebrafish model.
They were studying nerve - cell cilia in worms known as C. elegans.
Mice lacking normal cilia in parts of their brain that were important for memory had trouble remembering a painful shock.
The coiled - coiled domain containing protein CCDC151 is required for efficient motility of IFT dependant cilia in animals.
RFX3 governs growth and beating efficiency of motile cilia in mouse and controls genes involved in human ciliopathies.
The study shows lithium chloride, a drug often used to treat bipolar disorder, can increase the size of primary cilia in several cell types.

Not exact matches

Cilia participated in the Global Opportunity Panel in Oslo on 5th June 2015 and works as advisor on climate change and sustainability services for KPMG Norway.
There's a lot more in that vein from Behe, including descriptions of the cilia propulsion system in bacteria, the basic biochemistry of the immune system, and the cell's intricate internal transport system.
In a hatbox's tied and knotted fringe, fray and cilia of thread, bistre - washed in sepia, under the bed, the dead lay color - blind in shades of gray: each cordoned heart, veined - red, darkened as on alchemists» hands the nitrate silvereIn a hatbox's tied and knotted fringe, fray and cilia of thread, bistre - washed in sepia, under the bed, the dead lay color - blind in shades of gray: each cordoned heart, veined - red, darkened as on alchemists» hands the nitrate silverein sepia, under the bed, the dead lay color - blind in shades of gray: each cordoned heart, veined - red, darkened as on alchemists» hands the nitrate silverein shades of gray: each cordoned heart, veined - red, darkened as on alchemists» hands the nitrate silvered.
Applying many natural ingredients -LCB- that can which can that may -RCB- be found in associate cilium foil will facilitate motivate a natural thicker cilium.
β - arrestin, which has several known roles in signaling systems, also links a key receptor to a motor protein so that the receptor can be transported to cilia for sensing environmental cues.
In mammalian cells, Smo - dependent signaling requires translocation to primary cilia.
Researchers now have genetic evidence implicating faulty cellular antennas, called primary cilia, in shrinking the wings.
This multimeric complex localized to primary cilia and was disrupted in cells transfected with β - arrestin small interfering RNA.
The study, carried out in collaboration with the German company Cilia AG and published in the journal PLoS One, was funded by the European Union.
You tilt your head to one side and little calcium carbonate stones in your inner ear hit the cilia.
When fresh air was passed into the chamber, the researchers observed a 3 per cent drop in cilia beating frequency relative to the baseline value.
At even higher formaldehyde concentrations of 3.0 milligrams per cubic meter, however, the researchers observed an unexpected decrease in cilia beating frequency, possibly due to irreversible cell damage caused by the formaldehyde.
Barlow's film was widely circulated at European universities, and in 1978 the British Broadcasting Company (BBC) approached his advisor with an invitation to contribute his expertise on cilia to the David Attenborough series «Life on Earth.»
In contrast, when air mixed with 0.5 milligrams per cubic meter of formaldehyde was passed through the chamber, they observed a 7.4 per cent increase in cilia beating frequency relative to the baseline valuIn contrast, when air mixed with 0.5 milligrams per cubic meter of formaldehyde was passed through the chamber, they observed a 7.4 per cent increase in cilia beating frequency relative to the baseline valuin cilia beating frequency relative to the baseline value.
By enabling the observation of cilia beating frequency, the experimental model described in this work provides more realism for clinical applications.
Further increasing the formaldehyde concentration to 1 milligram per cubic meter led to a dramatic increase — up to 136.4 per cent — in cilia beating frequency relative to the baseline value.
The ability to escape from a dead end can be found in many kinds of microorganisms with cilia.
Cells in the airways have mobile cilia which sweep mucus and dirt out of the lungs, but almost every cell in the body has a primary (sensory) cilium.
In the early 2000s, cell biologists linked cyst formation to gene mutations that affect the primary cilia, hair - like projections from cells that seem to act as sensory antennae.
«Scientists are beginning to realise that primary cilia, which were once thought to be irrelevant are actually involved in a number of key biological processes,» explains co-author Professor Martin Knight from Queen Mary's School of Engineering and Materials Science and the Institute of Bioengineering.
Those deletions tended to involve genes that affect cilia, cellular structures that are important for signaling and patterning in embryonic development.
Microtubule bundles line the cilia — tiny, hairlike structures — of a paramecium, shown here both from the side and in cross section.
The scientists now believe that the loss of normal function in the primary cilium leads to the uncontrollable division of renal epithelial cells, which contributes to the formation of ccRCC.
Based on experiments with mice, some scientists had speculated that cilia nestled in a dimple at the top of the embryo called the node might push fluid down the left side of the embryo, carrying a signal that somehow triggers certain genes to activate.
In addition, he cautions that cilia - driven flow may not be a universal first step, as some evidence suggests that left - right differences in some animals begin before the formation of the node and ciliIn addition, he cautions that cilia - driven flow may not be a universal first step, as some evidence suggests that left - right differences in some animals begin before the formation of the node and ciliin some animals begin before the formation of the node and cilia.
New research suggests that fluid driven by tiny swirling hairs called cilia may activate certain genes in the growing embryo that lay the groundwork for this asymmetry.
That's why I think the mechanistic studies are so important to try to only target the TGF - beta receptor signaling in the primary cilia but not in other parts of the body,» says Ogretmen.
In the October 24, 2017 issue of Science Signaling, they showed that primary cilia act as a focal point to transmit growth signals.
Additionally, Bardet - Biedl syndrome is a metabolic disease in which trafficking of proteins within the cilium is blocked.
But it turns out that in at least six coral species, the cilia do much more.
Ciliopathies are caused by defects in cilia, finger - like projections from cells that act as microscopic «antenna» to detect and respond to chemical changes or fluid flow outside the cell.
Professor Colin A. Johnson, Professor of Medical and Molecular Genetics in the School of Medicine at the University of Leeds, said: «This research gives us the best list yet of the human genes needed to make cilia.
We then focused in on some of the biochemical processes that are required for a functioning cilium.
The isoforms beta ARK - 2 and beta - arrestin - 2 are highly enriched in and localized to the dendritic knobs and cilia of the olfactory receptor neurons where the initial events of olfactory signal transduction occur.
The fluid vortex shown is generated by cilia covering the coral's surface, creating a whirlpool structure in the surrounding seawater.
Scrutinizing the cells, Negulescu could see why: Lung cells are covered in fine hairlike structures called cilia.
Centrioles are tiny structures in the cell that play an important role in cell division and in the assembly of cilia and flagella.
It is not clear how this calcium signal might relate to mouse embryos, in which rotating cilia help set up left and right sides (ScienceNOW, 3 July, 2002).
Neurologist Kazunobu Sawamoto at Keio University in Japan and an international team of his colleagues used fluorescent dye and India ink to trace the flow of spinal fluid in mice and found that it followed the whiplike waving of hairlike projections known as cilia from cells lining the route.
Monk notes, however, that other studies have shown that the swishing cilia also influence calcium concentrations, and it is possible that a similar effect is at work in developing mice.
For his part, Katsanis says he predicts that taste, too, will soon be included in the cilia story: «It will be another area where cilia will surprise us.»
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