We now show that astrocytes generated from the same population of human fetal glial precursor cells, by exposure to either bone morphogenetic protein (BMP) or
ciliary neurotrophic factor (CNTF), promote widely divergent outcomes with respect to repairing the injured adult spinal cord.
We undertook, a couple of years ago, a phase one trial for one such neuro enhancing therapeutic called
ciliary neurotrophic factor or CNTF.
The regulation and activatin of
ciliary neurotrophic factor signaling proteins in adipocytes.
Yu said the impairment of sensory nerve regeneration in diabetic corneas is due to decreased
ciliary neurotrophic factor, as evidenced by the fact that dendritic cells express
ciliary neurotrophic factor (CNTF) in normal and healing corneas but decrease in diabetic corneas due to the reduced infiltration of dendritic cells.